Soy Foods Associated with Decreased Risk of Death in Women with Breast Cancer

JAMA — Abstract: Soy Food Intake and Breast Cancer Survival, December 9, 2009, Shu et al. 302 (22): 2437

Design, Setting, and Participants The Shanghai Breast Cancer Survival Study, a large, population-based cohort study of 5042 female breast cancer survivors in China. Women aged 20 to 75 years with diagnoses between March 2002 and April 2006 were recruited and followed up through June 2009. Information on cancer diagnosis and treatment, lifestyle exposures after cancer diagnosis, and disease progression was collected at approximately 6 months after cancer diagnosis and was reassessed at 3 follow-up interviews conducted at 18, 36, and 60 months after diagnosis. Annual record linkage with the Shanghai Vital Statistics Registry database was carried out to obtain survival information for participants who were lost to follow-up. Medical charts were reviewed to verify disease and treatment information.

Conclusion Among women with breast cancer, soy food consumption was significantly associated with decreased risk of death and recurrence.

Tofu anyone?

Byetta (exenatide) – Renal Failure Too

Byetta (exenatide) – Renal Failure

From April 2005 through October 2008, FDA received 78 cases of altered kidney function (62 cases of acute renal failure and 16 cases of renal insufficiency), in patients using Byetta. Some cases occurred in patients with pre-existing kidney disease or in patients with one or more risk factors for developing kidney problems.

Oops.

CRP Meta-Analysis

C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis : The Lancet

CRP concentration has continuous associations with the risk of coronary heart disease, ischaemic stroke, vascular mortality, and death from several cancers and lung disease that are each of broadly similar size. The relevance of CRP to such a range of disorders is unclear. Associations with ischaemic vascular disease depend considerably on conventional risk factors and other markers of inflammation.