Background: Pulmonary restriction is associated with increased mortality in adults, especially those who are elderly. Previous studies, however, have used the FVC as a surrogate for the total lung capacity (TLC). We evaluated the association between a reduced TLC, mortality, and health-care resources use and compared this association with a reduced FVC.
Conclusions: Reduced TLC is strongly associated with mortality in adults who are elderly. Reduction of the FVC is a weaker risk factor for mortality.
The Nigerian Federal Ministry of Health has reported an increased number of cases of Lassa fever. Nineteen of the country’s 36 states have reported cases since the beginning of 2012. As of April 13, 2012, there were reports of 818 suspected cases, including 84 deaths. At this time, 131 cases have been confirmed by laboratory testing. Seven deaths have also been reported among health care workers.
Avoid contact with rats, especially rat urine and feces. Put food away in rodent-proof containers.
- Keep the home clean and rodent proof.
- Trap rats in and around homes.
- Do not eat rats.
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The largest open long-term care insurance claim has reached $1.7 million in paid benefits, according to a just-released report from the American Association for Long-Term Care Insurance (www.AALTCI.org). The claimant, a woman, purchased coverage at age 43, paying an annual premium of $881. Three years later her long term care insurance claim began and has continued for almost 15 years.
In the current analysis, Elizabeth Devore, an instructor in medicine at Brigham and Women’s Hospital, and her colleagues addressed the gap in the research by reviewing the eating habits of a single cohort of 16,000 women participating in the Nurses Health Study. During their 50s and 60s, every four years the women answered questions by phone about what they ate. And in their 70s, they came into the lab for six different cognitive function tests. Devore and her team also had information on the women’s education, income and other socioeconomic factors that can affect cognitive function.
She and her colleagues focused their attention on berries because rodent studies showed that the key compound in berries, a flavonoid called anthocyanidin, could seep through the blood and into brain tissues — specifically concentrating in the hippocampus, which is responsible for learning and memory. As an antioxidant, flavonoids also fight inflammation and oxidation, both processes that affect aging brain cells.
Proscar is indicated for treatment of symptoms in men with benign prostatic hyperplasia (BPH) and also is approved to reduce urinary retention risk or the need for surgery related to BPH. Propecia is approved for use only in men as a treatment for male pattern baldness.
Among specific changes the FDA is calling for are:
- a revision to the Propecia label to add libido disorders, ejaculation disorders and orgasm disorders that continued after the drug was discontinued;
- a revision to the Proscar label to include decreased libido that continued after the drug was discontinued; and
- revisions to both drugs’ labels that describe reports of male infertility and/or poor semen quality that normalized or, at least, improved after discontinuing the respective drug.
According to the agency, the changes were based on its review of hundreds of case reports of sexual dysfunction that persisted after patients ceased using the drugs. It should be noted that in 2011, the FDA called for both drugs’ labels to be revised to include erectile dysfunction as a side effect that continued after discontinuation of the drug.