CHD

High Noise Levels and CHD

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Medical News: Noise on the Job Linked to CHD – in Cardiovascular, Myocardial Infarction from MedPage Today

There are several ways in which noise could contribute to cardiovascular events, according to the researchers. One is through the development of isolated diastolic hypertension, which has been shown to independently predict CHD and is more common among younger individuals.

The stress caused by loud noise also might lead to activation of the endocrine and sympathetic nervous systems, resulting in vasoconstriction, occlusion, and plaque disruption, they explained.

A limitation of the study was the possibility of selection bias. Workers who don’t tolerate noise or who have cardiovascular disease could have moved to other, less stressful jobs — or could have died while still in their noisy jobs.

Depression + CHD = Bad

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Medical News: Depression Plus Heart Disease Equal Lethal Combo – in Psychiatry, Depression from MedPage Today

The risk of all-cause mortality was elevated 67% for patients with coronary heart disease (P<0.05) and 2.10 times for those with depressive symptoms (P<0.001) in the long-running Whitehall II study of British civil servants.

But patients who had both conditions had a nearly five-fold risk compared with those who had neither (hazard ratio 4.99, P<0.001), Hermann Nabi, PhD, of the University of Versailles, France, and colleagues reported online in Heart.

Calcium Supplements and MI Risk

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Medical News: Risk of MI May Go Up With Calcium Supplements – in Cardiovascular, Myocardial Infarction from MedPage Today

Calcium supplementation appears to increase the risk of myocardial infarction, a meta-analysis showed.

Among studies of patients with or at risk for osteoporosis, those who took calcium supplements were about 30% more likely to have an MI than those who did not, Ian Reid, MD, of the University of Auckland in New Zealand, and colleagues reported online in BMJ.

Among randomized controlled trials with patient-level data, the hazard ratio for MI with supplementation was 1.31 (95% CI 1.02 to 1.67). Among those with trial-level data, the relative risk was 1.27 (95% CI 1.01 to 1.59).

HgbA1c and CVD

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Glycemic Control and Cardiovascular Disease in 7,454 Patients With Type 1 Diabetes — Diabetes Care

CONCLUSIONS This observational study of patients in modern everyday clinical practice demonstrates progressively increasing risks for CHD and CVD with higher A1C, independently of traditional risk factors, with no J-shaped risk curves. A baseline mean A1C of 7.2% showed considerably reduced risks of CHD and CVD compared with A1C 9.0%, emphasizing A1C as a strong independent risk factor in type 1 diabetes.