It’s not entirely clear how cannabis hyperemesis syndrome occurs though there are several theories. One is that since cannabinoids have long-half lives and are lipid soluble, they accumulate in the brain and over time cause symptoms, particularly in young people who may have genetic variations in enzymes which lead to further accumulation. Another theory is that there is a thermoregulatory and autonomic imbalance in the limbic system caused by chronic use. Other suggestions are that with long-term consumption cannabis becomes a receptor antagonist, or that they become down-regulated or de-sensitised over time. This reverses the antiemetic effect of cannabis. It seems that chronic over-stimulation of receptors leads to dysregulation of the body’s control of nausea and vomiting, leading to CHS.Owen Hibberd . What you need to know about Cannabinoid Hyperemesis Syndrome, Don’t Forget the Bubbles, 2022. Available at: https://doi.org/10.31440/DFTB.48627
I am so glad I never inhaled.
Protection with a Third Dose of mRNA Vaccine against SARS-CoV-2 Variants in Frontline Workers — https://www.nejm.org/doi/full/10.1056/NEJMc2201821?af=R&rss=currentIssue
No quotes provided because I want you to read the original article.
Researchers report nearly 300 cases of inflammatory syndrome tied to Covid-19 in kids
Addendum to Post Pandemic Changes in Consumer Behavior.
Home schooling. A lot more home schooling.
With approximately 1000 cases of MIS-C (including, here and below, those that have been classified as PIMS-TS) reported worldwide, do we now have a clear picture of the new disorder, or, as in the story of the blind men and the elephant, has only part of the beast been described? What are its cause and pathogenesis? How should it be diagnosed and treated, and are there wider implications for our understanding of Covid-19?
Link to the NEJM article.
COVID-19 in Kids: New Neurologic, Radiographic Findings
The president of Harvard University has tested positive for COVID-19
On Monday they were tested, and on Tuesday they received the results of the test.
I am beyond pissed off.
Healthcare workers can’t even get tested!