Researchers Figure Out Why Coffee Is Good For The Heart

The team focused on a protein called p27, which is known among other things to influence the cell cycle. The team found that caffeine triggered the movement of p27 into the mitochondria of heart cells in mice, and in particular, the migration of the heart’s endothelial cells, which line the blood vessels. How well the endothelial cells were able to migrate, they found, relied strongly on the presence of p27, which again is bolstered by caffeine. 

Read the Forbes article here.

Advertisements

Sleep Apnea Raises Your Risk of Sudden Cardiac Death

In a five-year study of nearly 11,000 people, those with obstructive sleep apnea had a higher risk of sudden cardiac death. At greatest risk were those aged 60 and older with moderate to severe apnea (20 episodes an hour).

When their oxygen saturation levels dipped below 78 percent — preventing air from flowing into the lungs — their risk increased by 80 percent.

Memo to Underwriters:

In case anyone asks why we are so harsh on untreated OSA quote this study.

Article link here.

Link to the study abstract here.

RESULTS:

During an average follow-up of 5.3 years, 142 patients had resuscitated or fatal SCD (annual rate 0.27%). In multivariate analysis, independent risk factors for SCD were age, hypertension, coronary artery disease, cardiomyopathy or heart failure, ventricular ectopy or nonsustained ventricular tachycardia, and lowest nocturnal O2sat (per 10% decrease, hazard ratio [HR]: 1.14; p = 0.029). SCD was best predicted by age >60 years (HR: 5.53), apnea-hypopnea index >20 (HR: 1.60), mean nocturnal O2sat <93% (HR: 2.93), and lowest nocturnal O2sat <78% (HR: 2.60; all p < 0.0001).

CONCLUSIONS:

In a population of 10,701 adults referred for polysomnography, OSA predicted incident SCD, and the magnitude of risk was predicted by multiple parameters characterizing OSA severity. Nocturnal hypoxemia, an important pathophysiological feature of OSA, strongly predicted SCD independently of well-established risk factors. These findings implicate OSA, a prevalent condition, as a novel risk factor for SCD.

Vitamin D and Mortality Risk in People With CVD

Summary:     A normal intake of vitamin D can reduce the risk of early death substantially in people with cardiovascular disease, a new study shows. The study concludes that people who have suffered from cardiovascular disease, and have a normal intake of vitamin D, reduce their risk of morality as a consequence of the disease by 30 per cent.

Source article can be found here.

Eat Yogurt

Higher intakes of yogurt were associated with a 30 percent reduction in risk of myocardial infarction among the Nurses’ Health Study women and a 19 percent reduction in the Health Professionals Follow-Up Study men.

In both groups, participants consuming more than two servings a week of yogurt had an approximately 20 percent lower risks of major coronary heart disease or stroke during the follow-up period. When revascularization was added to the total cardiovascular disease outcome variable, the risk estimates were reduced for both men and women, but remained significant.

Higher yogurt intake in combination with an overall heart-healthy diet was associated with greater reductions in cardiovascular disease risk among hypertensive men and women.

Read the source article here.

 

Eat More Cashews

Conclusion

Cashew nut supplementation in Asian Indians with T2DM reduced systolic blood pressure and increased HDL cholesterol concentrations with no deleterious effects on body weight, glycemia, or other lipid variables. This study was registered at the clinical trial registry of India as CTRI/2017/07/009022.

Cashew Nut Consumption Increases HDL Cholesterol and Reduces Systolic Blood Pressure in Asian Indians with Type 2 Diabetes: A 12-Week Randomized Controlled Trial

This explains why cashews are my favorite nut.

I’m the guy who picks out all of the cashews in a bowl of mixed nuts.

Mortality Falls After AF Ablation in Heart Failure

A majority of patients in the ablation group, about 63%, were in sinus rhythm at the 60-month follow-up, compared with only 22% (P<0.001) in the group with medically managed AF, “which suggests that maintenance of sinus rhythm is beneficial when achieved without the use of antiarrhythmic drugs,” write the authors, led by Dr Nassir F Marrouche (University of Utah Health, Salt Lake City).

Read the source article here.

 

Linking Sucrose to Hyperlipidemia and Cancer

In rats.  But it’s the behavior of the sugar industry rats that is more disturbing.

Read the entire study here.

Our study contributes to a wider body of literature documenting industry manipulation of science. Industries seeking to influence regulation have a history of funding research resulting in industry-favorable interpretations of controversial evidence related to health effects of smoking [15,16], therapeutic effects of pharmaceutical drugs [17,18], the relationship between sugar-sweetened beverage consumption and weight gain or obesity [5], and the causes of climate change, [19] among other issues. The tobacco industry also has a long history of conducting research on the health effects of its products that is often decades ahead of the general scientific community and not publishing results that do not support its agenda [2023]. This paper provides empirical data suggesting that the sugar industry has a similar history of conducting, but not publishing studies with results that are counter to its commercial interests.