Dr. Karb was in the same residency class at Brown as Dr. Lee.
I have much respect for Brownies.
That’s it. My only comment on the J&J vaccine blood clot risk.
While the data provide useful insights, they also remain subject to gaps, limitations, and inconsistencies that limit the ability to get a complete picture of who is and who is not getting vaccinated. For example, data gaps and separate reporting of data for vaccinations administered through the Indian Health Service limit the ability to analyze vaccinations among American Indian and Alaska Native people and Native Hawaiian and Other Pacific Islander. Moreover, some states have high shares of vaccinations that are missing race/ethnicity or that are classified as “other,” limiting the ability to interpret the data. For example, in Alaska, over 30% of vaccinations were among people classified as “other” race, and race was unknown for over 30% of vaccinations in Virginia. Four states were not reporting vaccination data by race/ethnicity, including Georgia which halted reporting its data in March. Comprehensive standardized data across states will be vital to monitor and ensure equitable access to and take up of the vaccine.Latest Data on COVID-19 Vaccinations Race/Ethnicity — https://www.kff.org/coronavirus-covid-19/issue-brief/latest-data-on-covid-19-vaccinations-race-ethnicity/
Meanwhile in Oklahoma…
Monica Gandhi MD, MPH is Professor of Medicine and Associate Division Chief (Clinical Operations/ Education) of the Division of HIV, Infectious Diseases, and Global Medicine at UCSF/ San Francisco General Hospital. She also serves as the Director of the UCSF Center for AIDS Research (CFAR) and the Medical director of the HIV Clinic at SFGH (“Ward 86”). Dr. Gandhi completed her M.D. at Harvard Medical School and then came to UCSF in 1996 for residency training in Internal Medicine. After her residency, Dr. Gandhi completed a fellowship in Infectious Diseases and a postdoctoral fellowship at the Center for AIDS Prevention Studies, both at UCSF. She also obtained a Masters in Public Health from Berkeley in 2001 with a focus on Epidemiology and Biostatistics.https://profiles.ucsf.edu/monica.gandhi
Seven out of eight emergency department (ED) visits attributed to adverse events from benzodiazepines involve self-harm or nonmedical use of these drugs, and more than 80% involve concurrent use of alcohol, illicit drugs, or other substances, new research shows.
Although benzodiazepines are typically not problematic in terms of acute overdoses when used alone, patients often don’t take them as prescribed or use them with other substances in a self-harm attempt, author Daniel S. Budnitz, MD, MPH, director of the Medication Safety Program, Centers for Disease Control and Prevention (CDC), told Medscape Medical News.
“Clinicians need to be aware of what other substances patients might be taking when they’re being prescribed a benzodiazepine,” Budnitz added.
The study was published online February 19 in the American Journal of Preventive Medicine.Benzodiazepines Implicated in High Rate of ED Visits Across US – Medscape – Feb 25, 2020 – https://www.medscape.com/viewarticle/925686#vp_1
“Major issues” that may have to be managed in the context of acute intoxication with propylhexedrine include severe agitation, tachycardia, hypertension, myocardial infarction, hyperthermia, stroke, bowel obstruction, pulmonary hypertension, and seizures, the FDA said.There is no specific agent for reversing the effects of acute propylhexedrine intoxication, so management is symptomatic and supportive, the FDA notes.Abuse of OTC Decongestant Potentially Deadly – https://www.medscape.com/viewarticle/948125?src=rss
This is an OTC decongestant I’ve never heard of nor used.
Somehow I missed this article from 2019 https://www.medscape.com/viewarticle/922914
“I took the medication only as prescribed,” Bobbi said. After her benzodiazepine was stopped abruptly, she suffered multiple disabling neurological symptoms, including seizures, cognitive and visual impairment, difficulty walking, and hand contractures, leaving her unable to work. Bobbi is one of many patients my advocacy organization helped report their harm to the FDA. Our goal was to raise awareness of the adverse effects of benzodiazepines and advocate for stronger warning labels.
Thus, I was pleasantly surprised last September to see the FDA’s drug safety communication announcing an update to the boxed warning for benzodiazepines “to address the serious risks of abuse, addiction, physical dependence, and withdrawal reactions.” Curious, I filed a FOIA request for the FDA’s 175-page report on benzodiazepines. Many of the document’s conclusions raise the same concerns benzodiazepine safety advocates have had for decades.updated benzodiazepine boxed warning: What you need to know — https://www.kevinmd.com/blog/2021/03/the-updated-benzodiazepine-boxed-warning-what-you-need-to-know.html
I downloaded the FDA report for future reference.
The report should be fun weekend reading.
Many thanks to Dr. Monica Gandhi for taking the time and effort to create this graphic.
Share this with everyone. I want the pandemic to be over.
That lump in your armpit may actually be a good thing. The study is a pre-print with a small number of study subjects.