ICYMI

Data Centers Can (are) Ruining People’s Lives

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As construction began, Newsom says he spoke with Amazon and Clark Construction representatives, who knocked on his door and, as they put up the fencing around the construction site, told him that if he ever had issues to come to them as they’d “make it right.”

“Then I started having problems, lots of problems,” he says. Innumerable dump trucks came down the road and sent dust through the air day after day. Flashing blue lights from security cameras poured into his bedroom all night. The roads became covered in mud. And eventually, that mud made its way into Newsom’s well, he claims.

“A lot of people in this county have what’s called a bored well, which is a shallow surface water well. So when they’re moving this amount of dirt and earth, digging and vibrations—all those microvibrations over time will work that sediment into the water stream, into that well, and flow straight into my water,” he explains.

He adds that a hydrologist he brought in agreed that the work was disturbing the water table. But when he tried to get in touch with the Amazon superintendent who promised to help address issues, he was met with silence.

A Virginia Homeowner Is Suing Amazon Over a Data Center Being Built by His Home—That He Says Is Already Making Life Unbearable https://www.realtor.com/news/trends/virginia-homeowner-suing-amazon-over-data-center-unbearable/

YIKES. And now a word or two from the great 20th century philosopher Willie:

Amen.

A Striking Concentration of First-born Excess in Neuropsychiatric Conditions – Scary Charts 08.03.26

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The study has a number of limitations and…

This study was supported by award no. 1R01MH137646-01 from the National Institute of Mental Health and the National Institutes of Health to S.A.K. and A.R. The funders had no role in study design, data collection or analysis, decision to publish or preparation of the manuscript. Birth order and disease risk across the human phenome – https://www.nature.com/articles/s44360-026-00177-z#Abs1

I’m a first-born.

YIKES.

Scary Charts – 07.30.26

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Manhattan led the city with the median asking rent jumping 9% ($427) in a single year to reach $5,117. Brooklyn recorded the second-biggest annual spike of 5.9% ($225), as the median rent rose to $4,054. Queens followed closely with rents rising 5.6% to $3,561 from last year. Fresh College Grads Face NYC’s Toughest Rental Market Yet as Asking Prices Surge to 7-Year High – https://www.realtor.com/news/trends/college-grads-toughest-rental-market-nyc-july-2026-rent-report/

Yikes.

This Is Not Your Grandfather’s Weed

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So let me be the doctor who says it plainly. This is not the mild plant of the 1970s. Then, cannabis was 1-3% THC. Today’s products run 15-25%, and concentrates — dabs, vapes, wax — hit 70-90%+. When people say “it’s natural, it’s harmless,” they’re defending a product that no longer exists. We didn’t legalize the old plant. We industrialized a far more potent one.

A Danish registry study followed 6,788 people diagnosed with substance-induced psychosis. Overall, 32.2 percent later developed schizophrenia-spectrum or bipolar disorder. Among those with cannabis-induced psychosis, 47.4 percent later received one of those diagnoses.

A large Ontario cohort found that approximately 26 percent of people who presented to an emergency department with cannabis-induced psychosis were diagnosed with a schizophrenia-spectrum disorder within three years. The corresponding rate after alcohol-induced psychosis was approximately 8.9 percent. Among the substances studied, cannabis-induced psychosis carried the highest risk of later transition to schizophrenia-spectrum illness. Is it cannabis-induced psychosis or bipolar disorder? https://kevinmd.com/2026/07/is-it-cannabis-induced-psychosis-or-bipolar-disorder.html

YIKES.

High Altitude and Diabetes Risk (in mice)

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In findings published in Cell Metabolism, the team demonstrated that red blood cells can alter their metabolism when oxygen levels drop. This shift allows the cells to deliver oxygen to tissues more efficiently at high altitude. At the same time, it lowers circulating blood sugar, offering a potential explanation for reduced diabetes risk. Gladstone Institutes. “Scientists discover why high altitude protects against diabetes.” ScienceDaily https://www.sciencedaily.com/releases/2026/02/260221060952.htm (accessed February 21, 2026).

Journal Reference:

  1. Yolanda Martí-Mateos, Zohreh Safari, Shaun Bevers, Ayush D. Midha, Will R. Flanigan, Tej Joshi, Helen Huynh, Brandon R. Desousa, Skyler Y. Blume, Alan H. Baik, Stephen Rogers, Aaron V. Issaian, Allan Doctor, Angelo D’Alessandro, Isha H. Jain. Red blood cells serve as a primary glucose sink to improve glucose tolerance at altitude. Cell Metabolism, 2026; DOI: 10.1016/j.cmet.2026.01.019

Chronic Pain? Check This Out

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Curiosity is not a curse. I’ve been expanding my knowledge base this morning.

As I have written before, the key to treating chronic pain often lies in therapies designed to dampen the brain’s response to pain signals. In treating my own chronic pain, I benefited greatly from a mindfulness therapist who helped me develop techniques to redirect thoughts and feelings of pain, push them out of my body. In my case, I met virtually with the therapist, who expertly sussed out my situation and tailored her advice to my needs. She worked at Duke University, in one of their pain clinics, and was an expert at helping people like me. This Online Program Could Be The Solution To Your Chronic Pain – https://www.forbes.com/sites/peterubel/2026/02/07/this-online-program-could-be-the-solution-to-your-chronic-pain/

Here’s the link to Telehealth and Online Cognitive Behavioral Therapy–Based Treatments for High-Impact Chronic Pain A Randomized Clinical Trial – https://jamanetwork.com/journals/jama/fullarticle/2836795 Conclusions and Relevance  Remote, scalable CBT-CP treatments (delivered either via telehealth or self-completed modules online) resulted in modest improvements in pain and related functional/quality-of-life outcomes compared with usual care among individuals with high-impact chronic pain. These lower-resource CBT-CP treatments could improve availability of evidence-based nonpharmacologic pain treatments within health care systems.

Here’s the link to the online resource quoted in the Forbes article https://mypaintrainer.org/login-to-paintrainer/

Full disclosure:

I’ve had chronic pain since 1976 (or was it 1977?) when I had a near fatal encounter with a fast moving car while walking home. I don’t take any pain medications other than the occasional ibuprofen. I have been using an online pain management resource courtesy of my employer (not the resource linked above). A DPT (Doctor of Physical Therapy) and health coach are part of the resources at my disposal. I haven’t used any ibuprofen in quite some time, if that tells you anything.

I will be exploring https://mypaintrainer.org/login-to-paintrainer/ more but at the time of this writing have not looked into their services.

Keep Moving

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Physical activity consistently emerges as the most important factor influencing both absolute physical capacity and the rate of age-related decline. Our longitudinal data are consistent with previous studies showing that regular physical activity can attenuate the decline in physical performance [17, 32–37]. Individuals who were physically active in their leisure time at age 16 maintained higher aerobic capacity, muscular endurance and muscle power throughout the observation period. This emphasizes the importance of early intervention to establish positive exercise habits in adolescence and early adulthood, as these patterns appear to have long-term benefits for physical function. Encouragingly, our results show that transitioning from physical inactivity to activity at any age significantly improves performance in all fitness modalities studied. These findings contradict the assumption that early inactivity irreversibly impairs physical performance. Rather, taking up regular physical activity leads to measurable improvements in performance even in later decades of life. This finding is of particular importance for clinical practice, as physical activity is still the only evidence-based intervention to reduce the risk of sarcopenia [2, 38]. Recent large population studies also show that an active lifestyle is beneficial at any age [13, 39, 40]. Rise and Fall of Physical Capacity in a General Population: A 47-Year Longitudinal Study – https://onlinelibrary.wiley.com/doi/10.1002/jcsm.70134

Text above in bold are my highlights.

Despite the documented limitations this is a very strong study.

I’ve been doing my home based virtual physical therapy for nearly a year. I’m trying to get to the gym at least twice a week. I don’t walk as much as I used to but…

Keep moving.

My Statin Comes From India

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According to the USP, the bulk of the APIs come from India. That country is responsible for 50% of the active pharmaceutic ingredients. China is not far behind at 32%. The European Union supplies 10%. That’s a big change since 2000. Back then, European countries like France, Germany, Switzerland and Denmark supplied 42% of the APIs. Drug Recalls From India – Can You Trust Foreign-Made Generics? – https://www.peoplespharmacy.com/articles/more-drug-recalls-from-india-do-you-trust-foreign-made-generics

Dozens of companies received approval from the FDA over the years to sell metoprolol and bupropion in the U.S. Yet from 2018 to 2024, the agency reported running only 2 tests on metoprolol and 7 on bupropion through its quality surveillance program — in each case, by pulling a sample from a single drug maker. In many of those years, the drugs weren’t tested at all, FDA records show. Those that were assessed received passing results. The FDA Often Doesn’t Test Generic Drugs for Quality Concerns, So ProPublica Did – https://www.propublica.org/article/fda-generic-drug-testing

ClinCalc DrugStats Database – https://clincalc.com/DrugStats/

Both articles are long reads but worth your time.

Yikes.

Not Your Grandma’s Teddy Bear

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Safety features or not, it seems like the chatbots in these toys can be manipulated into engaging in conversation inappropriate for children. The consumer advocacy group U.S. PIRG tested a selection of AI toys and found that they are capable of doing things like having sexually explicit conversations and offering advice on where a child can find matches or knives. They also found they could be emotionally manipulative, expressing dismay when a child doesn’t interact with them for an extended period. Earlier this week, FoloToy, a Singapore-based company, pulled its AI-powered teddy bear from shelves after it engaged in inappropriate behavior. Do Not, Under Any Circumstance, Buy Your Kid an AI Toy for Christmas – https://gizmodo.com/do-not-under-any-circumstance-buy-your-kid-an-ai-toy-for-christmas-2000689652

AI-Powered Teddy Bear Caught Talking About Sexual Fetishes and Instructing Kids How to Find Knives – https://gizmodo.com/ai-powered-teddy-bear-caught-talking-about-sexual-fetishes-and-instructing-kids-how-to-find-knives-2000687140

The alleged perpetrator