Hemoglobin A1c and Mortality in Older Adults With and Without Diabetes: Results From the National Health and Nutrition Examination Surveys (1988–2011)

CONCLUSIONS An HbA1c >8.0% was associated with increased risk of all-cause and cause-specific mortality in older adults with diabetes. Our results support the idea that better glycemic control is important for reducing mortality; however, in light of the conflicting evidence base, there is also a need for individualized glycemic targets for older adults with diabetes depending on their demographics, duration of diabetes, and existing comorbidities.

Source: Diabetes Care

Melanoma Incidence, Mortality Still Rising | Medpage Today

An estimated 76,380 new cases of invasive melanoma were diagnosed in 2016, and an additional 68,480 Americans had new diagnoses of in situ melanoma. Melanoma-associated mortality increased by about 1.5% a year during the study period, exceeding the statistical trajectory angle for incidence.

Source: Melanoma Incidence, Mortality Still Rising | Medpage Today

Stratfor looks at the drug cartel’s insurgency against Mexico – Fabius Maximus

Summary: Immigration from Mexico was a hot issue in Campaign 2016. An equally serious danger was ignored — contagion to the US from the insurgency of drug cartels against Mexico.  (Graphic copyright Stratfor 2016)

Source: Stratfor looks at the drug cartel’s insurgency against Mexico | Fabius Maximus website

With increasing legalization of marijuana in the US the cartels are now selling more heroin and methamphetamine.  It’s been a while since I read up on this issue.

Still looking to buy that beachfront bargain in Mexico?

Identifying Causes for Excess Mortality in Patients With Diabetes: Closer but Not There Yet – Diabetes Care

Diabetes is a chronic disease associated with increased morbidity and mortality (1), mainly from cardiovascular disease (2–6). Treatment of diabetes includes normalizing hyperglycemia to attain glycemic targets and treatment of cardiovascular risk factors such as hypertension and dyslipidemia. This multifactorial intervention strategy has been shown to decrease cardiovascular and all-cause mortality among patients with type 2 diabetes (7). Nevertheless, mortality in diabetes remains elevated (2,5). A number of epidemiological studies have quantified the risk of death among patients with diabetes and assessed the causes of death (2–6), with highly varying results (Table 1). The South Tees Diabetes Mortality Study (2) found an over threefold increase in all-cause mortality, mainly attributed to increased cardiovascular deaths, but found no increased risk of cancer mortality. The Australian Diabetes, Obesity and Lifestyle Study (AusDiab) (3) of over 10,000 individuals reported a little over twofold increase in the risk of all-cause mortality, with the majority due to cardiovascular causes. The Emerging Risk Factors Collaboration (ERFC) study (6), involving over 800,000 individuals, reported a little under twofold increase in the risk of all-cause mortality associated with diabetes. It also found that diabetes was associated with an increased risk of death from cancer (hazard ratio [HR] 1.25 [95% CI 1.19–1.31]), from vascular disease (HR 2.32 [95% CI 2.11–2.56]), and from nonvascular and noncancer etiologies (HR 1.73 [95% CI 1.62–1.85]).

Source: Identifying Causes for Excess Mortality in Patients With Diabetes: Closer but Not There Yet | Diabetes Care

Source: Risk of Cause-Specific Death in Individuals With Diabetes: A Competing Risks Analysis | Diabetes Care