Contemporary Assessment of Left Ventricular Diastolic Function in Older Adults Clinical Perspective | Circulation

Conclusions: Our findings suggest that left ventricular longitudinal relaxation velocity declines as a part of healthy aging and is largely prognostically benign. The use of age-based normative values when considering an elderly population improves the risk discrimination of diastolic measures for incident HF or death.

Source: Contemporary Assessment of Left Ventricular Diastolic Function in Older AdultsClinical Perspective | Circulation

Prognostically benign!

Metformin Use in Populations With CKD, CHF, or CLD – Annals of Internal Medicine -American College of Physicians

Conclusion: Metformin use in patients with moderate CKD, CHF, or CLD with hepatic impairment is associated with improvements in key clinical outcomes. Our findings support the recent changes in metformin labeling.

Source: Metformin Use in Populations With CKD, CHF, or CLD | Annals of Internal Medicine | American College of Physicians