Social Isolation Transforms the Brain

In mice.

Confirming and extending previous observations, the researchers showed that prolonged social isolation leads to a broad array of behavioral changes in mice. These include increased aggressiveness towards unfamiliar mice, persistent fear, and hypersensitivity to threatening stimuli. For example, when encountering a threatening stimulus, mice that have been socially isolated remain frozen in place long after the threat has passed, whereas normal mice stop freezing soon after the threat is removed. These effects are seen when mice are subjected to two weeks of social isolation, but not to short-term social isolation — 24 hours — suggesting that the observed changes in aggression and fear responses require chronic isolation.

Though the work was done in mice, it has potential implications for understanding how chronic stress affects humans.

Get out of the house.  Socialize with friends and family.  Leave the cell phone at home.

Social media is not social.  It’s a serious public health problem for the brainwashed masses with addictive behaviors.

Read the source article here.

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Vitamin B12 Breakthrough for more complete Vegetarian and Vegan diets

Vitamin B12 (known as cobalamin) is an essential dietary component but vegetarians are more prone to B12 deficiency as plants neither make nor require this nutrient.

But now a team, led by Professor Martin Warren at the University’s School of Biosciences, has proved that common garden cress can indeed take up cobalamin.

The amount of B12 absorbed by garden cress is dependent on the amount present in the growth medium, and the Kent team was able to confirm B12 uptake by showing that the nutrient ends up in the leaf.

I can’t wait for the silly money and marketers to grab this and run.

Read the source article here.

 

Vegan Diet Rapidly Improves Type 2 Diabetes Markers in Adults

The 16-week randomized controlled trial in 73 adults showed that participants who ate a diet of vegetables, grains, legumes, and fruits significantly improved their overall metabolic condition, say Hana Kahleova, MD, PhD, of the Physicians Committee for Responsible Medicine in Washington, DC, and colleagues.

Previous studies have shown that the prevalence of diabetes is 46% to 74% lower in people who eat a plant-based diet compared with meat lovers in the general population, according to background information in the article.

A vegan diet has also been shown to improve glycemic control in type 2 diabetes better than calorie-restricted, low-carbohydrate diets, the researchers note.

You can access the Medscape article here.

This is a link to the online abstract.

Reminder — Beer, wine and whiskey are vegan!

Sleep Apnea Raises Your Risk of Sudden Cardiac Death

In a five-year study of nearly 11,000 people, those with obstructive sleep apnea had a higher risk of sudden cardiac death. At greatest risk were those aged 60 and older with moderate to severe apnea (20 episodes an hour).

When their oxygen saturation levels dipped below 78 percent — preventing air from flowing into the lungs — their risk increased by 80 percent.

Memo to Underwriters:

In case anyone asks why we are so harsh on untreated OSA quote this study.

Article link here.

Link to the study abstract here.

RESULTS:

During an average follow-up of 5.3 years, 142 patients had resuscitated or fatal SCD (annual rate 0.27%). In multivariate analysis, independent risk factors for SCD were age, hypertension, coronary artery disease, cardiomyopathy or heart failure, ventricular ectopy or nonsustained ventricular tachycardia, and lowest nocturnal O2sat (per 10% decrease, hazard ratio [HR]: 1.14; p = 0.029). SCD was best predicted by age >60 years (HR: 5.53), apnea-hypopnea index >20 (HR: 1.60), mean nocturnal O2sat <93% (HR: 2.93), and lowest nocturnal O2sat <78% (HR: 2.60; all p < 0.0001).

CONCLUSIONS:

In a population of 10,701 adults referred for polysomnography, OSA predicted incident SCD, and the magnitude of risk was predicted by multiple parameters characterizing OSA severity. Nocturnal hypoxemia, an important pathophysiological feature of OSA, strongly predicted SCD independently of well-established risk factors. These findings implicate OSA, a prevalent condition, as a novel risk factor for SCD.

What You Should Know About Lipoprotein(a) And Heart Attack Risk

Great post.

The Skeptical Cardiologist

If you have had a heart attack at an early age or one of your parents did but your standard risk factors for coronary heart disease are normal you should consider getting tested for Lipoprotein(a) or Lp(a).

The standard lipid profile that most patients get checks LDL (bad) HDL (good) and total cholesterol along with  triglycerides. While these are useful, I have many patients who have normal standard values but have developed advanced coronary heart disease at an early age despite following a perfect lifestyle (not smoking, regular aerobic exercise, healthy diet.)

The skeptical cardiologist tests such patients for Lp(a) (pronounced LP little a)  and it is quite frequently elevated.

For patients, these are the facts to know about Lp(a)

  1. It is the strongest single inherited (monogenetic) risk factor for the early development of coronary artery disease, heart attacks and strokes.
  2. In addition to increasing risk of atherosclerosis, high Lp(a)…

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Walmart is Big Brother is Amazon

This whole surveillance state thing is just plain creepy.

It is perfectly clear that patients are going to get some kind of a grade from The Walmart Enforcement Agency and you’d better believe that there will be consequences if that grade isn’t good. Good luck getting a legal prescription filled there if you don’t make the grade. Pharmacies around the country are already arbitrarily deciding who does or does not get their scripts filled. Although is not explicitly stated it a pretty safe bet that patients could be refused prescriptions because of their score doesn’t meet Walmart’s “standards.”

I wonder what George Orwell would say.

Read the article here.

Experts Say Keep Amazon’s Alexa Away From Your Kids

Hey Alexa.  Brainwash my children.

Hey Alexa, What Are You Doing to My Kid’s Brain?

Hey Alexa.  What are you doing to my kid’s brain?

When Teens Cyberbully Themselves (another reason to take the phone away)

Recent research and clinical psychologists now suggest that some adolescents are engaging in a newer form of self-aggression — digital self-harm. They’re anonymously posting mean and derogatory comments about themselves on social media.

Digital self-harm.

Parents – take the phone away.

Very interesting article.  HT to naked capitalism.