Linking Sucrose to Hyperlipidemia and Cancer

In rats.  But it’s the behavior of the sugar industry rats that is more disturbing.

Read the entire study here.

Our study contributes to a wider body of literature documenting industry manipulation of science. Industries seeking to influence regulation have a history of funding research resulting in industry-favorable interpretations of controversial evidence related to health effects of smoking [15,16], therapeutic effects of pharmaceutical drugs [17,18], the relationship between sugar-sweetened beverage consumption and weight gain or obesity [5], and the causes of climate change, [19] among other issues. The tobacco industry also has a long history of conducting research on the health effects of its products that is often decades ahead of the general scientific community and not publishing results that do not support its agenda [2023]. This paper provides empirical data suggesting that the sugar industry has a similar history of conducting, but not publishing studies with results that are counter to its commercial interests.

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Gastric Cancer Risk Doubled With Long-term PPI Use

Source: Gastric Cancer Risk Doubled With Long-term PPI Use

The study was published online October 31 in Gut.

The researchers point out, however, that this was an observational study, which can’t prove cause and effect.

A strength of the study is its use of data from a large population-based database with complete information on subsequent diagnoses and drug prescriptions, which minimizes selection, information, and recall biases, the researchers say. Use of strict exclusion criteria as well as propensity score adjustment to control for potential confounders and restricting the sample to patients with successful H pylori eradication are other strengths.

In terms of study weaknesses, the researchers  lacked information on some risk factors, such as diet, family history, and socioeconomic status.  And despite the large sample of more than 63,000 H pylori–infected patients, the small number of gastric cancer cases did not allow for any “meaningful evaluation of the dosage effect and role of different PPIs,” the researchers say.

A common herbal medicine may cause liver cancer mutations | New Scientist

A commonly-used herbal medicine causes mutations that are linked to liver cancer, according to research in Taiwan. Extracts taken from plants of the genus Aristolochia, which are used in traditional Chinese medicine to treat a wide range of conditions, may be responsible for many liver cancers in Asia.

Source: A common herbal medicine may cause liver cancer mutations | New Scientist

Death Rate From Liver Cancer in US Now Double That in 1980s

Modifiable Risk Factors

Approximately 60% of all liver cancers in the United States are caused by potentially modifiable risk factors, the researchers indicate. For example, it has been estimated that among Medicare recipients, the largest proportion of cases of HCC, at 32%, are caused by metabolic disorders, including obesity. A smaller proportion of cases of HCC are caused by hepatitis C virus infection (21%), excessive alcohol intake (13%), and smoking (9%).

 

Source: Death Rate From Liver Cancer in US Now Double That in 1980s