diabetes
Hypoglycemia in DM2 = Higher Mortality Risk
Type 2 diabetes patients who experienced these serious drops in blood glucose had nearly three times the risk of death and twice the risk of a major macrovascular event compared with those who didn’t experience hypoglycemia, Sophia Zoungas, MD, PhD, of the University of Sydney in Australia, and colleagues reported in the New England Journal of Medicine.
T2DM and Cognitive Decline
Type 2 Diabetes and Cognitive Decline in Middle-Aged Men and Women — Diabetes Care
CONCLUSIONS Middle-aged individuals with type 2 diabetes showed a greater decline in cognitive function than middle-aged individuals without diabetes.
Can Postchallenge Glucose, Fasting Glucose and A1c Predict T2DM?
RESULTS Incidence of diabetes during the follow-up was 17.1%. Two of three of the cases of newly diagnosed diabetes were predicted by a raise in ≥1 of the markers. Elevated A1C, IGT, or IFG preceded diabetes in 32.8, 40.6, and 21.9%, respectively. CVD was predicted by an intermediate and diabetic range of 2-h glucose but only by diabetic A1C levels in women.
CONCLUSIONS A1C predicted 10-year risk of type 2 diabetes at a range of A1C 5.7–6.4% but CVD only in women at A1C ≥6.5%.
Lower T2DM Risk With Veggies
Medical News: Green Veggies Cut Diabetes Risk – in Endocrinology, Diabetes from MedPage Today
Increasing the daily intake of green leafy vegetables could significantly reduce the risk of type 2 diabetes, a British meta-analysis found.
Consuming 1.35 servings of these vegetables per day was associated with a 14% reduction in risk compared with consuming only 0.2 servings (HR 0.86, 95% CI 0.77 to 0.96, P=0.01), according to Patrice Carter, a PhD student at the University of Leicester, and colleagues.
Time to Rethink HOS Void Times in T2DM
The study showed that measuring albumin:creatinine ratio from a first-void urine sample is more accurate for predicting progression of kidney disease in type 2 diabetics than are other commonly used measures.
DM2 Up in Vietnam
BBC News – Fast food ‘fuelling Asia diabetes boom’
A study by Australian and Vietnamese scientists found about 11% of men and 12% of women in Vietnam’s Ho Chi Minh City had undiagnosed type 2 diabetes.
Metformin May Lower Mortality in T2DM Patients
Medical News: ADA: Mortality Lower with Metformin – in Meeting Coverage, ADA from MedPage Today
A large, multicenter trial found a 24% reduced risk of all-cause mortality among patients on the drug, compared with those not taking it, according to Ronan Roussel, MD, PhD, of Groupe Hospitalier Bichat-Claude Bernard in Paris, and colleagues.
HgbA1c and CVD
Glycemic Control and Cardiovascular Disease in 7,454 Patients With Type 1 Diabetes — Diabetes Care
CONCLUSIONS This observational study of patients in modern everyday clinical practice demonstrates progressively increasing risks for CHD and CVD with higher A1C, independently of traditional risk factors, with no J-shaped risk curves. A baseline mean A1C of 7.2% showed considerably reduced risks of CHD and CVD compared with A1C 9.0%, emphasizing A1C as a strong independent risk factor in type 1 diabetes.
Hemoglobin A1c Levels Differ in Black and White Persons Independent of Glucose Level
Glucose-Independent, Black–White Differences in Hemoglobin A1c Levels — Ann Intern Med
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