FDA Warns Chantix May Up Heart Risk

A meta-analysis ordered by the agency and conducted by drugmaker Pfizer found a higher occurrence of major adverse cardiovascular events — including death, MI, and stroke — with the drug than with placebo.

The FDA noted, however, that such events were uncommon in both groups, and the increased risk wasn’t statistically significant.

via Chantix May Up Heart Risk, FDA Warns.

Quitting smoking is good.  Maybe quitting smoking without a pharmaceutical assist is better.  Additional link to the FDA release follows.

Safety Alerts for Human Medical Products > Chantix (Varenicline): Safety Communication – Updated Safety Review On The Risk of Cardiovascular Adverse Events.

When the Patient Is ‘Noncompliant’ – NYTimes.com

Despite efforts to change the term to the slightly more accurate “nonadherent,” the word “noncompliant” remains firmly entrenched in the medical lexicon. No matter what it’s called, however, it’s an enormous problem. Experts estimate that some 50 percent of patients do not take their medicines as prescribed or follow doctors’ recommendations.

via When the Patient Is ‘Noncompliant’ – NYTimes.com.

Underwriting and mortality issue?  I think so.

U.S. Diabetes Prevalence Soars

From 1995 to 2010, the median age-adjusted prevalence of diagnosed diabetes for all 50 states, the District of Columbia (D.C.), and Puerto Rico rose from 4.5% to 8.2% Linda Geiss, MA, of the CDC, and colleagues reported in the Nov. 16 issue of Morbidity & Mortality Weekly Report.

via U.S. Diabetes Prevalence Soars.

and MMWR link Increasing Prevalence of Diagnosed Diabetes — United States and Puerto Rico, 1995–2010.

Maybe the demise of Twinkies wasn’t such a bad thing after all.