Deaths From Narcotic Painkillers Quadrupled in Past Decade: CDC – WebMD.
Deaths from overdoses of drugs such as hydrocodone (Vicodin), morphine and oxycodone (Oxycontin) climbed from 1.4 per 100,000 people to 5.4 per 100,000, according to the U.S. Centers for Disease Control and Prevention.
That means about 3,000 people died in 1999 from unintentional overdoses. By 2011, that number was up to nearly 12,000 deaths, the report said.
If you read the source article you’ll never look at constipation the same way ever again. Better dig deeper to find out why your applicant is constipated. It may not be just a horrible diet and lack of dietary fiber.
And yet another FDA approved drug to counteract adverse effects from another FDA approved drug.
FDA Okays Naloxegol Movantik in Opioid-Induced Constipation.
The US Food and Drug Administration (FDA) has approved naloxegol (Movantik, AstraZeneca Pharmaceuticals), a peripherally acting opioid receptor antagonist, for the treatment of opioid-induced constipation (OIC) in adults with chronic noncancer pain.
OIC is a common adverse effect of opioid use. An estimated 40% to 80% of patients receiving long-term opioid therapy experience OIC, which can be severe enough to cause discontinuation of opioid therapy.
British pair found murdered on Thai resort.
“It was the first time this has happened on the island. I have never seen anything like this,” the staff member added, requesting anonymity.
No, it is not the first time. See second article.
Their deaths take to 13 the number of British visitors to Thailand murdered in the past five years in what the Foreign Office calls “vicious, unprovoked attacks by gangs”.
HT – Helen Vangikar and Jim Wigmore.
A whole bunch of winos in France and Italy.
FDA Approves Bupropion/Naltrexone Contrave for Obesity.
If I’m understanding this correctly we now have an anti-depressant combined with a drug originally approved for treating opioid, then alcohol addiction, approved by the FDA to treat obesity.
This will be interesting.
UPDATE
Obesity drugs have side effects. The reason it’s taken three years for the FDA to approve NB32/Contrave is that obesity drugs have serious side effects. So serious, in fact, that several major diet drugs have been yanked from the market, making doctors, regulators and yes, investors shy away. Cardiovascular disease and mood problems are just two of the potentially serious side effects associated with Qsymia and Belviq. Older drugs Xenical and Alli carry a risk of permanent liver and kidney damage. And those weight loss supplements you buy over the counter? Some are deadly.
via Contrave: Is This The Weight Loss Drug We’ve Been Waiting For?.
Like I said, this will be interesting.
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Researchers analyzed registry data from some 800 patients with liver injury either from medications excluding acetaminophen or herbal and dietary supplements. In the first 2 years of the registry, 7% of cases were due to herbal and dietary supplements, a proportion that increased to 20% a decade later. Hepatotoxicity from non-bodybuilding-related supplements required liver transplantation more often than injury from conventional drugs 13% vs. 3%; there were no cases of liver transplantation associated with bodybuilding supplements.
via Increases in Liver Injury Related to Herbal and Dietary Supplements — Physician’s First Watch.
Melanoma Risk Appears Doubled in Airline Pilots, Cabin Crew — Physician’s First Watch.
Researchers analyzed data from 19 trials comprising over 250,000 participants. They found that pilots and cabin crew workers had roughly twice the risk for melanoma as the general population — a finding that held true for both men and women. Pilots and cabin crew members also had a 42% increased risk for melanoma mortality. – See more at: http://www.jwatch.org//fw109248/2014/09/04/melanoma-risk-appears-doubled-airline-pilots-cabin-crew#sthash.q9tTZsuy.dpuf
In Bariatric Surgery, Sleeve Gastrectomy Now More Common than Bypass — Physician’s First Watch.
The authors examined data on some 44,000 patients undergoing surgery in a 39-hospital Michigan collaborative. From 2008 to 2013, the prevalence of sleeve gastrectomy rose from about 6% to 67% of bariatric procedures. The Roux-en-Y approach dropped from 58% to 27%; adjustable banding fell from 35% to 5%. – See more at: http://www.jwatch.org//fw109242/2014/09/03/bariatric-surgery-sleeve-gastrectomy-now-more-common#sthash.4m9BIpud.dpuf
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