There have been hundreds of reports of acute and chronic pancreatitis from people who have taken drugs such as Mounjaro, Ozempic and Wegovy, although none are confirmed as being caused by the medicines. Weight loss jabs study begins after reports of pancreas issues – https://www.bbc.com/news/articles/c4ged0r1n3wo
Yikes.
Californians voted to legalize recreational pot in 2016. Three years later, emergency room visits for cannabis-induced psychosis went up 54% across the state, from 682 to 1,053, according to state hospital data. For people who already have a psychotic disorder, cannabis makes things worse — leading to more ER visits, more hospitalizations, and more legal troubles, said Dr. Deepak Cyril D’Souza, a psychiatry professor at Yale University School of Medicine who also serves on the physicians’ advisory board for Connecticut’s medical marijuana program.
California May Require Labels on Pot Products to Warn of Mental Health Risks — https://khn.org/news/article/california-marijuana-warning-labels/
Listen to the article above here: https://www.npr.org/sections/health-shots/2022/06/17/1105494283/california-pot-warning-labels
Recreational cannabis use is linked to a heightened risk of emergency care and hospital admission for any cause, finds research published in the open access journal BMJ Open Respiratory Research.
Cannabis use linked to heightened emergency care and hospital admission risks — https://medicalxpress.com/news/2022-06-cannabis-linked-heightened-emergency-hospital.html
It’s not entirely clear how cannabis hyperemesis syndrome occurs though there are several theories. One is that since cannabinoids have long-half lives and are lipid soluble, they accumulate in the brain and over time cause symptoms, particularly in young people who may have genetic variations in enzymes which lead to further accumulation. Another theory is that there is a thermoregulatory and autonomic imbalance in the limbic system caused by chronic use. Other suggestions are that with long-term consumption cannabis becomes a receptor antagonist, or that they become down-regulated or de-sensitised over time. This reverses the antiemetic effect of cannabis. It seems that chronic over-stimulation of receptors leads to dysregulation of the body’s control of nausea and vomiting, leading to CHS.
Owen Hibberd . What you need to know about Cannabinoid Hyperemesis Syndrome, Don’t Forget the Bubbles, 2022. Available at: https://doi.org/10.31440/DFTB.48627
I am so glad I never inhaled.
“I took the medication only as prescribed,” Bobbi said. After her benzodiazepine was stopped abruptly, she suffered multiple disabling neurological symptoms, including seizures, cognitive and visual impairment, difficulty walking, and hand contractures, leaving her unable to work. Bobbi is one of many patients my advocacy organization helped report their harm to the FDA. Our goal was to raise awareness of the adverse effects of benzodiazepines and advocate for stronger warning labels.
Thus, I was pleasantly surprised last September to see the FDA’s drug safety communication announcing an update to the boxed warning for benzodiazepines “to address the serious risks of abuse, addiction, physical dependence, and withdrawal reactions.” Curious, I filed a FOIA request for the FDA’s 175-page report on benzodiazepines. Many of the document’s conclusions raise the same concerns benzodiazepine safety advocates have had for decades.
updated benzodiazepine boxed warning: What you need to know — https://www.kevinmd.com/blog/2021/03/the-updated-benzodiazepine-boxed-warning-what-you-need-to-know.html
I downloaded the FDA report for future reference.
The report should be fun weekend reading.
The Centers for Disease Control and Prevention said at present it looks like anaphylaxis cases are occurring at a rate of about 5.5 per 1 million vaccine doses given, though the agency cautioned that figure may change as the vaccination effort continues.
The allergic reactions do not change CDC’s recommendations on who can be vaccinated against Covid-19, with senior officials stressing that the risk of severe illness and death from the disease still outweighs the risk of developing anaphylaxis after vaccination.
CDC reports more allergic reactions to Covid-19 vaccines, but cases remain few — https://www.statnews.com/2021/01/06/cdc-reports-more-allergic-reactions-to-covid-19-vaccines-but-cases-remain-few/?utm_campaign=rss
Get jabbed.
Attention-deficit/hyperactivity disorder (ADHD) exerts lifelong impairment, including difficulty sustaining employment, poor credit, and suicide risk. To date, however, studies have assessed selected samples, often via self-report. Using mental health data from the entire Swedish population (N = 11.55 million) and a random sample of credit data (N = 189,267), we provide the first study of objective financial outcomes among adults with ADHD, including associations with suicide. Controlling for psychiatric comorbidities, substance use, education, and income, those with ADHD start adulthood with normal credit demand and default rates. However, in middle age, their default rates grow exponentially, yielding poor credit scores and diminished credit access despite high demand. Sympathomimetic prescriptions are unassociated with improved financial behaviors. Last, financial distress is associated with fourfold higher risk of suicide among those with ADHD. For men but not women with ADHD who suicide, outstanding debt increases in the 3 years prior. No such pattern exists for others who suicide.
Science Advances
30 Sep 2020:
Vol. 6, no. 40, eaba1551
DOI: 10.1126/sciadv.aba1551 — https://advances.sciencemag.org/content/6/40/eaba1551
Here in the US we’ve seen an steady increase in ADHD diagnoses.
And an alarming increase in suicide.
Then my mind wanders to drugs (to drugs, not due to drugs).
To summarize, the psychiatric side effects of methylphenidate are quite similar to those of cocaine and amphetamines, giving more support to the idea that almost all CNS stimulants will produce a similar clinical picture. A person using cocaine can experience nervousness,57,58 restlessness,58 agitation,57 suspiciousness,60 paranoia,61–63 hallucinations and delusions,61,63 impaired cognitive functions,64 delirium,65 violence,57,58,62,65,66 suicide,67 and homicide.67–70
Methylphenidate Abuse and Psychiatric Side Effects — http://Prim Care Companion J Clin Psychiatry. 2000 Oct; 2(5): 159–164. doi: 10.4088/pcc.v02n0502
I just hope I’m wrong.
Link to the full article here.
Benadryl isn’t safe
Benadryl causes significant sedation. One study in a driving simulator showed an ordinary adult dose of Benadryl caused worse driving than a blood alcohol level of 0.1 percent (that’s between buzzed-drunk and frat-party drunk). Ordinary doses of Benadryl can also cause urinary retention, dizziness, trouble with coordination, dry mouth, blurry vision, and constipation. Especially in older individuals, diphenhydramine can cause delirium and contribute to long term dementia.
You be the judge.
Go to the following link for a list of SGLT2 Inhibitors.
An Update on SGLT2 Inhibitors for the Treatment of Diabetes Mellitus
Fournier Gangrene does not sound like a pleasant disease.
Read a quick history lesson here.
Read about psychosis risk here.
Pass the doobie please.
Regardless of the century, physicians throughout the ages have known that real medicines carry risks. Any truly medicinal substance is able to give a little whack to one or more bodily processes. The goal is to whack the body back into normal functioning. That’s basically what medicine is all about – strategically whacking our physiology. But anything capable of whacking (which is to say any real medicine) is capable of harming at least a few of the many patients who would take it. This fact is so non-negotiable that we have a name for doctors who claim to have discovered effective medicines that don’t have any risks: we call them quacks.
Source: Ten Drugs Make New FDA Watch List
Side effects under investigation.
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