Get FIT!

Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide.

In this retrospective, population-based, descriptive cohort study, organized FIT-based screening was associated with a sustained decline in CRC mortality, particularly among individuals aged 50 to 69 years. Colorectal Cancer Mortality Following an Organized Fecal Immunochemical Test–Based Screening Programhttps://jamanetwork.com/journals/jamanetworkopen/fullarticle/2852451

Underlying Causes and Causal Pathways are Largely Unknown (guess the disease)

Using high-quality population-based cancer registry data until 2017, this study presents contemporary trends in early-onset colorectal cancer incidence across 50 countries and territories, including 12 additional countries (Argentina, Bahrain, Belarus, Chile, Columbia, Ecuador, France [Martinique], Iceland, Kuwait, the USA [Puerto Rico], Qatar, and Uganda) since the last published report on colorectal cancer incidence trends. The findings show that the rising incidence of early-onset colorectal cancer is no longer limited to high-income countries; it now extends to countries and territories in Latin America and the Caribbean (Argentina, Chile, Costa Rica, Ecuador, Martinique, and Puerto Rico), Asia (Israel, Japan, Thailand, and Türkiye), and eastern Europe (Belarus). Colorectal cancer incidence trends in younger versus older adults: an analysis of population-based cancer registry datahttps://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00600-4/fulltext

Yikes.