Mild Hyperparathyroidism = Higher All Cause Mortality

Medical News: BES: ‘Mild’ Parathyroid Disease Poses Mortality Risk – in Meeting Coverage, BES from MedPage Today

Compared with the general population, the relative risk of all-cause mortality in patients with clinically minimal hyperparathyroidism was 2.62 (95% CI 2.39 to 2.86) in a population-based study, according to Graham Leese, MD, of the University of Dundee in Scotland.

Undiagnosed CKD in Prediabetes

Medical News: Kidney Disease Common in Undiagnosed and Prediabetes – in Nephrology, General Nephrology from MedPage Today

More than 40% of people with undiagnosed diabetes had chronic kidney disease, based on albuminuria or reduced estimated glomerular filtration rate (eGFR) — just as many as in those with diagnosed diabetes, according to Laura C. Plantinga, ScM, of San Francisco General Hospital and University of California San Francisco, and colleagues.

Notably, 56.2% of chronic kidney disease was stage 3 or 4 among those with prediabetes, indicated by a fasting plasma glucose between 100 and 126 mg/dl, and for whom kidney dysfunction was likely unsuspected.

Don’t Take Plavix if You Are a Poor Metabolizer

A “poor metabolizer” does not effectively convert Plavix to its active form because of low CYP 2C19 activity.

How does someone figure out they are a “poor metabolizer”?

Read the FDA communication if you’re seriously interested in the answer to this question.

FDA Drug Safety Communication: Reduced effectiveness of Plavix (clopidogrel) in patients who are poor metabolizers of the drug

The U.S. Food and Drug Administration (FDA) has added a Boxed Warning to the label for Plavix, the anti-blood clotting medication. The Boxed Warning is about patients who do not effectively metabolize the drug (i.e. “poor metabolizers”) and therefore may not receive the full benefits of the drug.

Remote Work – Who Are Those Guys?

What are the Top 10 nations for online workers? / The Christian Science Monitor – CSMonitor.com

And the fastest-growing major economy for freelance work?

The United States. “We’re seeing a huge number of Americans come online,” says Brian Goler, vice president of marketing for oDesk. “More and more people are working this way.”

Perhaps they have to because of the economic downturn. Perhaps they want to.

Outsourcing v. Permanent Hires

Calculated Risk: Diffusion Index and Temporary Help

The thinking is that before companies hire permanent employees following a recession, employers will first increase the hours worked of current employees and also hire temporary employees. Since the number of temporary workers increased sharply, some people think this might be signaling the beginning of an employment recovery.

However, there has been some evidence of a shift by employers to more temporary workers, and the saying may become “We are all temporary now!”, so use this increase with caution. For more, including some cautionary comments from a BLS economist on using temporary help, see Tom Abate’s article in the San Francisco Chronicle.

The problem, of course, is the fact that temps and perma-temps are the first to be terminated at the beginning of a business cycle downturn and the first to be hired when the cycle turns back upwards.  If you’re a temp, that is.  Read the entire SF Chronicle article.  It’s a good, short read.