Conclusion: Hepatic steatosis is associated with a greater intake of fat and fried foods, whereas visceral obesity is associated with increased consumption of sugar and reduced consumption of fiber in overweight and obese adolescents at risk of type 2 diabetes. This study was registered at clinicaltrials.gov as NCT00755547.
underwriting
Higher BMI May Be Better for Older Adults
The association between all-cause mortality and BMI created a U-shaped curve with a broad base (P-nonlinearity <0.001). The “nadir of the curve for BMI and mortality was between 24.0 and 30.9, with the lowest risk being between 27.0 and 27.9 (HR 0.90, 95% CI 0.88-0.92),” wrote Caryl A. Nowson, PhD, of Deakin University in Melbourne, Australia, and her co-authors, in the American Journal of Clinical Nutrition.
They said that mortality risk did not increase with excess weight in this population until BMI was ≥33 (HR 1.08 for BMI of 33.0-33.9, 95% CI 1.00-1.15).
Risk of mortality was highest at a BMI lower than 23, the authors said. Using a BMI of 23.0 to 23.9 as the reference, there was a 12% greater risk of mortality for those with a BMI in the range of 21.0-21.9 (HR 1.12, 95% CI 1.10-1.13) and a 19% greater risk for those with a BMI in the range of 20.0-20.9 (HR 1.19, 95% CI 1.17-1.22), the authors said.
via Higher BMI May Be Better for Older Adults.
BMI and all-cause mortality in older adults: a meta-analysis.
Clinically Relevant Herb-Drug Interactions—Lecture by Dr. Bill Gurley | NCCAM
Clinically Relevant Herb-Drug Interactions—Lecture by Dr. Bill Gurley | NCCAM.
Budget an hour for this lecture.
Teens Likely to Get Opioid Rx for Headaches
The study, which was published in the Journal of Adolescent Healthanalyzed medical claims and pharmacy data from 8,373, 13- to 17-year-olds who visited a clinician for headache, which is a common ailment in adolescents.
Forty-six percent received one prescription for an opioid; 23% got two prescriptions and 29% got three or more prescriptions.
Flavonoid-rich Fruit and Vegetables Improve Microvascular Reactivity and Inflammatory Status
Results: In men, the HF F&V diet increased endothelium-dependent microvascular reactivity P = 0.017 with +2 portions/d at 6 wk and reduced C-reactive protein P = 0.001, E-selectin P = 0.0005, and vascular cell adhesion molecule P = 0.0468 with +4 portions/d at 12 wk. HF F&Vs increased plasma NO P = 0.0243 with +4 portions/d at 12 wk in the group as a whole. An increase in F&Vs, regardless of flavonoid content in the groups as a whole, mitigated increases in vascular stiffness measured by PWA P = 0.0065 and reductions in NO P = 0.0299 in the control group.
Mom was right.
Killing Pain: Script by Script
Primary care doctors wrote about 53 million benzodiazepine prescriptions in 2013, roughly four times the number written by psychiatrists, a group that penned 13 million benzo scripts.
Nurse practitioners and physician assistants were close behind with 11 million prescriptions for the drugs, according to data obtained by MedPage Today and the Milwaukee Journal Sentinel.
In 2013, non-doctors wrote 30 million opioid prescriptions, compared with 92 million written by primary care doctors that year, according to data provided by IMS Health, a drug market research firm.
In 2010, the most recent year for which data were available, 30% of the 16,651 people who died of an opioid overdose also had taken a benzodiazepine, according to the U.S. Centers for Disease Control and Prevention.
via Killing Pain: Script by Script.
Pancreatitis May Confer Higher Risk for Cancer
In an effort to quantify the relationship between acute pancreatitis and pancreatic cancer, Agarwal and colleagues reviewed inpatient and outpatient records for 495,504 patients who received care through the Veterans Health Administration from 2000 through 2007. The authors identified 5,720 patients who had one or more episodes of acute pancreatitis, 710 of whom subsequently had diagnoses of pancreatic cancer.
Median follow-up was 60 months for the entire cohort, 26 months for patients who developed pancreatic cancer, and 60 months for patients who did not develop pancreatic cancer.
The patient cohort was predominately male (89%). A third of the patients smoked, a fourth had a history of heavy alcohol use, and 3% had a history of gallstones.
The 710 patients included 86 who had one or more episodes of acute pancreatitis prior to cancer diagnosis. The authors found that 76 of the 86 patients had a least one episode of acute pancreatitis within 2 years of cancer diagnosis.
In 69 of the 76 cases, the preceding pancreatitis occurred within a year of pancreatic cancer diagnosis. In fewer than half of the cases (N=34), acute pancreatitis preceded pancreatic cancer diagnosis by 2 months or less.
The alarming rise of Adderall in two charts
Zika Fever in New Caledonia !
Zika fever is an illness caused by a virus that spread through mosquito bites. It is closely related to dengue virus and causes a similar illness. Symptoms of Zika fever may include fever, headache, red eyes, rash, muscle aches, and joint pains. The illness is usually mild and lasts 4-7 days.
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