Thankfully, we’ve learned from our mistakes. Opening blocked vessels is useful in really only two general areas:

Heart attack, where the rule of thumb is to open the tightest blockage (we refer to it as the “infarct-related artery”) and leave the rest as is.

Symptomatic blockages such as the 99% plug that caused my patient his troubles. If, on the other hand, a person has no chest pain or breathing difficulty associated with the disease, we provide no benefit by uncorking it—even if the blockage is 100%.

via Meaningful treatments in the battle against coronary disease.