Diabetes is a chronic disease associated with increased morbidity and mortality (1), mainly from cardiovascular disease (2–6). Treatment of diabetes includes normalizing hyperglycemia to attain glycemic targets and treatment of cardiovascular risk factors such as hypertension and dyslipidemia. This multifactorial intervention strategy has been shown to decrease cardiovascular and all-cause mortality among patients with type 2 diabetes (7). Nevertheless, mortality in diabetes remains elevated (2,5). A number of epidemiological studies have quantified the risk of death among patients with diabetes and assessed the causes of death (2–6), with highly varying results (Table 1). The South Tees Diabetes Mortality Study (2) found an over threefold increase in all-cause mortality, mainly attributed to increased cardiovascular deaths, but found no increased risk of cancer mortality. The Australian Diabetes, Obesity and Lifestyle Study (AusDiab) (3) of over 10,000 individuals reported a little over twofold increase in the risk of all-cause mortality, with the majority due to cardiovascular causes. The Emerging Risk Factors Collaboration (ERFC) study (6), involving over 800,000 individuals, reported a little under twofold increase in the risk of all-cause mortality associated with diabetes. It also found that diabetes was associated with an increased risk of death from cancer (hazard ratio [HR] 1.25 [95% CI 1.19–1.31]), from vascular disease (HR 2.32 [95% CI 2.11–2.56]), and from nonvascular and noncancer etiologies (HR 1.73 [95% CI 1.62–1.85]).
Author: SupremeCmdr
FDA Adds New Warnings to All Testosterone Product Labels
Testosterone and other AAS, which have a schedule III classification by the Controlled Substances Act, may be abused by adults and adolescents, including athletes and body builders.
“Abuse of testosterone, usually at doses higher than those typically prescribed and usually in conjunction with other AAS, is associated with serious safety risks affecting the heart, brain, liver, mental health, and endocrine system,” the FDA notes.
Reported serious adverse outcomes include myocardial infarction, heart failure, stroke, depression, hostility, aggression, liver toxicity, and male infertility. People abusing high doses of testosterone have also reported withdrawal symptoms, such as depression, fatigue, irritability, loss of appetite, decreased libido, and insomnia, the agency says.
Source: FDA Adds New Warnings to All Testosterone Product Labels
It is interesting you no longer see those Low-T commercials on television any more. Really? Just another clever marketing campaign to create a disease that doesn’t exist along with a convenient drug based solution. What side effects?
Read this book. Now.
Source: Bill Moyers Journal . Profile . Melody Petersen | PBS
One in four older adults is non-adherent to antihypertensive medications – APhA DrugInfoLine
Genworth Sold to China-based Firm – Richmond Times
The top executive at Genworth Financial Inc. assured analysts and investors Monday that the proposed sale to a China-based investment firm was “the best option” to preserve and create value for shareholders.
Genworth, a major seller of home mortgage insurance and long-term care insurance, announced Sunday evening that its board agreed for the Henrico County-based company to be bought for about $2.7 billion by Beijing-based China Oceanwide Holdings Group, a privately held international financial company that has been expanding its holdings in the U.S.
Snoopy Has Been Fired by MetLife – WSJ
MetLife decided earlier this year to part with most of its U.S. life-insurance business. Now it is cutting ties with Snoopy.
Source: Snoopy Has Been Fired by MetLife – WSJ
Could the Gecko be next???
The Oklahoman link is to their online comics section for October 21, 2016.
Scroll to the bottom of the page for the Peanuts strip.
Adderall at the Office: Millennials Take Their Addiction to the Workplace — Quartz
Phosphodiesterase type-5 inhibitor use in type 2 diabetes is associated with a reduction in all-cause mortality – Heart
Diagnosing PE in Pregnant Women — Brown Emergency Medicine
Epidemiology – Venous thromboembolism (VTE) occurs in pregnant women at 7-10 times the incidence in age-matched controls. Pregnant women who get VTE have deep venous thrombosis (DVT) approximately 3 times as often as pulmonary embolism (PE). The increased risk is similar during all three trimesters, starts to diminish after delivery, and returns to baseline by six weeks post-partum. The left leg is affected in 85% of pregnancy-associated DVT, possibly from compression of the left iliac vein. Isolated pelvic DVT is also more common in pregnancy. In the developed world, pregnancy-associated VTE is the leading cause of maternal mortality.
Source: Diagnosing PE in Pregnant Women — Brown Emergency Medicine
Study highlights drug-drug interaction risk from two commonly used drugs – Pharmaceutical Journal
Combined treatment with the antibiotic ceftriaxone and the proton pump inhibitor lansoprazole can lead to an increased risk of drug-induced arrhythmia, a study has found.
George Washington University Opens Food Pantry To Address Student Hunger : The Salt : NPR
George Washington University — one of the nation’s most expensive schools — is among the latest to try to make sure its students, most of whom receive financial aid, have enough to eat.
Source: George Washington University Opens Food Pantry To Address Student Hunger : The Salt : NPR
Why open food pantries???
Why not LOWER TUITION AND FEES?
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