CHD
JAMA – Nonobstructive Coronary Artery Disease and Risk of Myocardial Infarction
JAMA Network | JAMA | Nonobstructive Coronary Artery Disease and Risk of Myocardial Infarction.
Conclusions and Relevance In this cohort of patients undergoing elective coronary angiography, nonobstructive CAD, compared with no apparent CAD, was associated with a significantly greater 1-year risk of MI and all-cause mortality. These findings suggest clinical importance of nonobstructive CAD and warrant further investigation of interventions to improve outcomes among these patients.
Let’s Stop the Unnecessary Treatment of Heart Disease
Let’s Stop the Unnecessary Treatment of Heart Disease.
A recent population-based prospective studyof Swedish men suggested almost four of five MIs in men could be preventable.[1](That’s not a typo.) Researchers from the Institute of Environmental Medicine in Stockholm, Sweden, followed 20 721 men from 1997 to 2009. They specifically asked about five modifiable lifestyle behaviors: a healthy diet, moderate alcohol consumption, no smoking, being physically active, and having no abdominal fat (waist circumference.) There were 1361 cases of MI in the 11-year follow-up period.
heartwire journalist Michael O’Riordan recaps the details of the study here. The short story was that each of the five low-risk behaviors independently reduced the chance of having a heart attack. Not smoking was the strongest risk reducer. Men who combined all five behaviors were 86% less likely than those who had zero behaviors to have a heart attack.
Cardiology Conundrum: Aspirin for Primary Prevention
Cardiology Conundrum: Aspirin for Primary Prevention.
If you’re confused, read or listen to this interview. You’ll still be confused, but much more knowledgeable on the topic.
Does Aspirin Prevent CVD and Cancer? Ignore the Guidelines.
Then read this article to increase your confusion and become even more more knowledgeable on the topic.
Statins: The Good, the Bad, and the Unknown
Five Lessons From the Niacin Failure
Five Lessons From the Niacin Failure.
Niacin With Statins? No Dice..
HPS2-THRIVE: As Niacin Fails, HDL’s Role Is Debated Anew.
Enjoy these articles. Taking niacin? Well…
ASCVD Risk Estimator
Fruit, Veg Intake Has Dose-Response Link With CV Death
The inverse association between increased fruit and vegetable consumption and mortality was particularly noticeable for cardiovascular mortality; higher consumption was not significantly linked with reduced risk of cancer mortality
All of the pitfalls of the component studies are present in the meta-analysis, the authors warn, including the fact that fruit and vegetable intake is typically self-reported. Not all studies adjusted for other types of foods consumed, including saturated fats, processed meats, etc. The definition of “portions” may also have been different across studies, the authors caution.
via Fruit, Veg Intake Has Dose-Response Link With CV Death.
Vegans and radical vegetarians take note. Bold in quote above is my emphasis.
Diabetes and the Heart: Risk Greater in Women
Diabetes and the Heart: Risk Greater in Women.
Data from 64 studies with both male and female participants yielded a 44% greater multiple-adjusted relative risk ratio (RRR) for incident coronary heart disease (CHD) in women compared with men (RRR 1.44, 95% CI 1.27-1.63), Rachel Huxley, DPhil, of the University of Queensland in Sydney, Australia, and colleagues found.
Pooled data from 52 studies indicated that women also had a 44% greater chance than men of dying from fatal CHD associated with diabetes, Huxley and colleagues reported online in the journal Diabetologia.
Daily Aspirin – Yes or No?
Aspirin: FDA Says ‘No’ Others Say ‘Yes’.
I found this article quite helpful in my own decision regarding whether or not to continue my daily aspirin 81 mg dose.
The bump I gave myself on the shin a few weeks ago that bled profusely and took hours to clot was also quite helpful in my decision regarding whether or not to continue my daily aspirin 81 mg dose.
Update 06.06.14
Check out the following link. If you’re an older male you might find this of interest.
http://www.webmd.com/erectile-dysfunction/news/20110303/regular-use-of-painkillers-linked-to-ed
Update 07.26.14
This link takes you to the 2012 Circulation article.
Update 08.04.14
More links for your reading and research pleasure.
Aspirin May Not Protect Against Cardiovascular Disease – Prevention.com.
Benefits of aspirin more modest than previously believed — St George’s, University of London.
Researchers from Professor Kausik Ray’s group at St George’s, University of London investigated the drug’s effectiveness in primary prevention and the prevalence of side effects. They also assessed if aspirin had any impact on the risk of death from cancer among people considered at risk of cardiovascular disease.
They analysed data from nine clinical trials involving over 100,000 participants without a history of cardiovascular disease. Half of the participants took aspirin and half took a placebo. The average participant in the aspirin arm of these trials took aspirin for about six years.
The researchers found that although aspirin in conventional daily or alternate day doses reduced the risk of total cardiovascular disease events by 10 per cent, this was largely due to a reduction in non-fatal heart attacks. It did not include a reduction in other cardiovascular disease events including death from heart attack, or fatal or non-fatal stroke.
The study also showed that this benefit was almost entirely offset by a 30 per cent increase in risk of life-threatening or debilitating internal bleeding events. This means that while one cardiovascular disease event was averted for every 120 people treated with aspirin for about six years, one in 73 people suffered from potentially significant bleeding during the same period.
lifeunderwriter.net 
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