Physician’s Weekly provides news & information online and at the point-of-care to hospitals, oncology centers & physician group practices, including specialty editions for Surgery, Emergency Departments, Oncology & Primary Care.
Source: Non-Obstructive CAD & Heart Attack Risks | Physician’s Weekly for Medical News, Journals & Articles
via Stroke Rounds: Long Work Hours, Stroke and CHD Risk Associated | Medpage Today.
“Working 55 hours or more a week was associated with significant 33% increase in stroke risk and a more modest 13% increase in risk of developing coronary heart disease, compared to working 35 to 40 hours weekly, in the analysis of published and previously unpublished prospective cohort studies from the U.S., Europe, and Australia.”
One could argue for causation given the strength of association identified by this study. Common sense tells us that anyone working more than 60 hours a week is going to have considerably less time for other activities like exercise and time with family and friends. Long hours working also can lead to neglect of one’s health.
There are multiple links in the WP article to the original studies.
FDA Stiffens Warning on NSAID Cardiovascular Risk | Medpage Today.
Thought I would add a link to the actual FDA alert.
NSAIDs can increase the risk of heart attack or stroke in patients with or without heart disease or risk factors for heart disease. A large number of studies support this finding, with varying estimates of how much the risk is increased, depending on the drugs and the doses studied.
Untreated Sleep Apnea Boosts Risk of Heart Disease, Stroke | Medpage Today.
Compared with OSA-negative patients, untreated OSA was associated with an 86% higher mortality risk (adjusted hazard ratio 1.86, 95% CI 1.81 to 1.91), and treated OSA was associated with a 35% higher mortality risk (aHR 1.35, 95% CI 1.21 to 1.51), wrote Miklos Z. Molnar, MD, PhD, of the University of Tennessee Health Science Center in Memphis, and colleagues, in the journal Thorax.
Untreated OSA also was associated with a 3.5 times higher risk of incident coronary heart disease (aHR 3.54, 95% CI 3.40 to 3.69), and a 3.5 times higher risk of incident strokes (aHR 3.48, 95% CI 3.28 to 3.64), while treated OSA was associated with a threefold higher risk of incident CHD (aHR 3.06, 95% CI 2.62 to 3.56) and 3.5-fold higher risk of incident strokes (aHR 3.50, 95% CI 2.92 to 4.19). The risk of incident kidney disease also was significantly higher in untreated (aHR 2.27, 95% CI 2.19 to 2.36) and treated OSA (aHR 2.79, 95% CI 2.48 to 3.13).
The typical heart in aquatic invertebrate animals such as clams, oysters, and mussels has many strong similarities to the human heart. The Arctica islandica, or ocean quahog, is the longest-living, non-colony-dwelling animal ever identified; so far, the oldest identified specimen survived to age 508 (age is identified by counting shell growth rings).
via North Atlantic Clam That Lives for Centuries Yields Insights on Cardiac Aging | NCCIH.
“When we see something that surprises us and flies in the face of what is understood, it requires another look — maybe a different cohort, larger numbers, longer follow-up,”
via Intensive Tx Fails to Slow Atherosclerosis | Medpage Today.
Surprised? As long as we continue to focus on pharmaceuticals as the answer, no one should be surprised.
More on the aspirin debate.
Should patients stop taking aspirin for primary prevention? : Cleveland Clinic Journal of Medicine.
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