Source: An Estimated 2 Million U.S. Adults Have an Opioid Use Disorder — Physician’s First Watch
Pharma
Trends in Prescription Opioids Detected in Fatally Injured Drivers in 6 US States: 1995–2015 | AJPH | Ahead of Print
Results. The prevalence of prescription opioids detected in fatally injured drivers increased from 1.0% (95% confidence interval [CI] = 0.5, 1.4) in 1995 to 7.2% (95% CI = 5.7, 8.8) in 2015 (Z = −9.04; P < .001). Prescription opioid prevalence was higher in female than in male drivers (4.4% vs 2.9%; P < .001). Of the drivers testing positive for prescription opioids, 30.0% had elevated blood alcohol concentrations (≥ 0.01 g/dL), and 66.9% tested positive for other drugs.
Houston…we have a problem.
Two Generic Medications Become One Expensive Drug – The Atlantic
Early Glycemic Control and Magnitude of HbA1c Reduction Predict Cardiovascular Events and Mortality
CONCLUSIONS: A large initial HbA1c reduction and achievement of low HbA1c levels within 6 months after metformin initiation are associated with a lower risk of cardiovascular events and death in patients with type 2 diabetes.
Source: Diabetes Care
Ten Drugs Make New FDA Watch List
Source: Ten Drugs Make New FDA Watch List
Side effects under investigation.
Drugs for Diabetic Peripheral Neuropathy Pain — Physician’s First Watch
Metformin for Prediabetes – The JAMA Network
How Much Are Docs Responsible for Patients’ Opioid Abuse? – Medpage Today
F. Perry Wilson, MD, looks at the data on how patients get hooked
Source: How Much Are Docs Responsible for Patients’ Opioid Abuse? | Medpage Today
And if you’re having trouble falling asleep one night here’s the link to the source study.
Source: Incident and long-term opioid therapy among patients with ps… : PAIN
Immune system, unleashed by cancer therapies, can attack organs – American Pharmacists Association
Immunotherapy drugs have been regarded as a breakthrough in cancer treatment, but as their use grows, doctors are finding that they pose serious risks. A separate paper found that 30% of patients experienced “interesting, rare, or unexpected side effects,” with a quarter of the reactions described as severe, life-threatening, or requiring hospitalization. Some patients have died…Problems with the pancreas have been particularly unusual, causing patients typically aged 50 years and older to lose insulin production all at once.
Source: Immune system, unleashed by cancer therapies, can attack organs | American Pharmacists Association
Oops.
FDA Adds New Warnings to All Testosterone Product Labels
Testosterone and other AAS, which have a schedule III classification by the Controlled Substances Act, may be abused by adults and adolescents, including athletes and body builders.
“Abuse of testosterone, usually at doses higher than those typically prescribed and usually in conjunction with other AAS, is associated with serious safety risks affecting the heart, brain, liver, mental health, and endocrine system,” the FDA notes.
Reported serious adverse outcomes include myocardial infarction, heart failure, stroke, depression, hostility, aggression, liver toxicity, and male infertility. People abusing high doses of testosterone have also reported withdrawal symptoms, such as depression, fatigue, irritability, loss of appetite, decreased libido, and insomnia, the agency says.
Source: FDA Adds New Warnings to All Testosterone Product Labels
It is interesting you no longer see those Low-T commercials on television any more. Really? Just another clever marketing campaign to create a disease that doesn’t exist along with a convenient drug based solution. What side effects?
Read this book. Now.
Source: Bill Moyers Journal . Profile . Melody Petersen | PBS
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