Vitamin D Level Predicts Death in CABG

Patients with vitamin D deficiency or insufficiency, defined by levels of 25(OH)D, had significantly higher 90-day mortality after CABG than those who had sufficient levels of the vitamin (OR 5.24 and OR 4.61, respectively), Takuhiro Moromizato, MD, of Brigham and Women’s Hospital in Boston, and colleagues reported during an oral session at the Society of Critical Care Medicine meeting.

The study was limited by its observational design, which can’t prove causality, and by the potential for selection bias and unmeasured confounders.

via Vitamin D Level Predicts Death in CABG.

Is Running Bad for Your Heart? – NewsOK.com

A study published in the December issue of the British medical journal Heart looked at 52,600 people over three decades, and it found that those who ran more than 20 to 25 miles per week lived no longer than those who didn’t exercise at all. Another recent study also found that people who ran faster than 7 minutes and 30 seconds per mile when they exercised enjoyed no mortality advantage over couch potatoes. But in both studies, people who ran regularly, but at shorter distances and slower paces, lived longest.

via Is running bad for your heart? | NewsOK.com.

Yet another study that adds to the conflicting data we already have.  For the record, I no longer run for exercise.  But my excuse is OA.

Binge Drinking Among Women and High School Girls — United States, 2011

Results: Among adult women, the prevalence of binge drinking was 12.5%, and among those who binge drank, the frequency of binge drinking was 3.2 episodes per month and the intensity was 5.7 drinks on occasion. Binge drinking was most prevalent among women aged 18–24 years (24.2%) and 25–34 years (19.9%), and among those from households with annual incomes of ≥$75,000 (16.0%). Among those who binge drank, women aged 18–24 years had the highest frequency (3.6 episodes) and intensity (6.4 drinks) of binge drinking. Among high school girls, the prevalence of current alcohol use was 37.9%, the prevalence of binge drinking was 19.8%, and the prevalence of binge drinking among girls who reported current alcohol use was 54.6%.

Conclusions: Binge drinking is reported by one in eight U.S. adult women and one in five high school girls. Women who binge drink tend to do so frequently and with high intensity. Most high school girls who reported current alcohol use also reported binge drinking.

via Vital Signs: Binge Drinking Among Women and High School Girls — United States, 2011.

To Revert Breast Cancer Cells, Squeeze

While the traditional view of cancer development focuses on the genetic mutations within the cell, Mina Bissell, Distinguished Scientist at the Berkeley Lab, conducted pioneering experiments that showed that a malignant cell is not doomed to become a tumor, but that its fate is dependent on its interaction with the surrounding microenvironment. Her experiments showed that manipulation of this environment, through the introduction of biochemical inhibitors, could tame mutated mammary cells into behaving normally.

via To revert breast cancer cells, give them the squeeze.