There is a significant association between lowering uric acid in patients with high levels and a reduction of their mortality from cardiovascular disease, researchers said here.
During the study period, hyperuricemia patients who were treated with urate lowering drugs such as allopurinol achieved a 44% reduction in death caused by heart disease and a 58% reduction in deaths caused by stroke (P<0.001 for both), according to Jiunn-Horng Chen, MD, PhD, of China Medical University, Taichung, Republic of China (Taiwan).
Smoking and Dementia Risk
Conclusions – In this large cohort, heavy smoking in midlife was associated with a greater than 100% increase in risk of dementia, AD, and VaD more than 2 decades later. These results suggest that the brain is not immune to long-term consequences of heavy smoking.

Think Brand Strategy NOT Social Media Strategy
Sanders Says – You don’t need a social media strategy
Sanders Says – Brand strategy first, social media tactics second
You don’t need a social media strategy – You need a brand strategy that leverages social media. Don’t get off the brand strategy just because there’s a new communications channel, that’s how you lose the plot as a brand. Technology is the tail, not the dog.
Here are two links to two blog posts by Tim Sanders. If your company is struggling with social media these articles will help.
Richard Lehman’s Journal Review 11/1/10 & 10/25/10
BMJ Group blogs: BMJ » Blog Archive » Richard Lehman’s journal review – 1 November 2010
BMJ Group blogs: BMJ » Blog Archive » Richard Lehman’s journal review, 25 October
Sorry for the late link. I’ve been busy.
Death Toll in Mexico Tops 31,000 – The War to Our South
Duloxetine Hydrochloride (Cymbalta) – It’s Not Just for Depression Anymore
Why Some People Shouldn’t Drink Alcohol
Interesting x-ray.
Scary Chart of the Day – 10/29/10
Calculated Risk: Housing Bust impacting Manager Mobility
One of the strengths of the U.S. labor market has been the flexibility associated with labor mobility at all levels of employment – households could easily move from one region to another for better employment. The sharp decline in house prices, leaving homeowners with significant negative equity, appears to be limiting this flexibility.
It’s Saturday morning and I’m not sufficiently caffeinated, sitting in my office catching up on the news when I come across this chart. So I get up and get another cup of Joe, sip and think a little more about just what this chart is telling me.
A lot.
Dabigatran = Pradaxa for Atrial Fibrillation
The anticoagulant drug dabigatran (Pradaxa) was cleared for market for preventing strokes and thrombosis in patients with atrial fibrillation, the FDA announced.

Hospital Admissions for Drug Reactions = 65,000 Annually
The report, released by the Department of Health and Human Services’ (HHS) Agency for Healthcare Research and Quality (AHRQ) found that there was a major increase in hospital discharges from effects of both prescription and over-the-counter medications, as well as illegal drugs, among adults ages 45 and older.
Hospital admissions for drug-related conditions grew from about 30,000 per year to more than 65,000 per year — a 117% increase — between 1997 and 2008 for people ages 45 to 64, according to the report.


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