Effect of Two Intensive Statin Regimens on Progression of Coronary Disease — NEJM.
CHD risk factors
QT Interval Duration and Mortality
Watch those QT’s.
Conclusion: Shortened and prolonged QT-interval durations, even within a reference range, are associated with increased mortality risk in the general population.
ADHD Drugs and CV Events
ADHD Drugs and Serious Cardiovascular Events in Children and Young Adults — NEJM
In conclusion, in our study involving children and young adults with 2.5 million person-years of follow-up, there were 3.1 serious cardiovascular events per 100,000 person-years. Although the point estimates of the relative risks for ADHD drugs did not indicate increased risk, the upper limit of the 95% confidence interval suggested that a doubling in the risk could not be ruled out. However, the absolute magnitude of any increased risk would be low.
The entire article is worth reading given the potential serious side effects of the drugs in question.
Statins and Myopathy Risk
A1C – Not Just for DM
Taking Asprin? Don’t Stop
Medical News: Aspirin Holiday Is a Bad Idea – in Cardiovascular, Prevention from MedPage Today
A case-control study found that patients taking low-dose aspirin for secondary prevention who had recently discontinued the drug had a higher risk of nonfatal myocardial infarction than those who continued to take the aspirin.
Mom Was Right – Eat Your Veggies
Predictive Ability of CRP Questioned
Medical News: AHA: Value of Measuring CRP Questioned – in Meeting Coverage, AHA from MedPage Today
“In patients who already have a reason to be on a statin, C-reactive protein (CRP) measurement does not appear to provide any additional information about cardiovascular risk beyond traditional factors, a secondary analysis of the ASCOT trial showed.”
Silent Heart Damage and Cocaine
“Heavy cocaine users have a high prevalence of cardiac damage as seen by cardiac MRI.”
Gen X – What Happened?
“The coronary heart disease death rate for men ages 25 to 29 is now noticeably higher than it was in 1997 – and the highest it has been since about 1972.”
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