Kidney Disease = Possible Risk for MI

In a large cohort study, patients with only CKD had a significantly higher rate of myocardial infarction (MI) than those who only had diabetes (5.4 versus 6.9 per 1,000 person-years, P

Those who’d already had an MI had the highest overall rate of MI (18.5 per 1,000 person-years), they reported online in The Lancet.

via Medical News: Kidney Disease May Point to Risk for MI – in Cardiovascular, Myocardial Infarction from MedPage Today.

Undiagnosed CKD in Prediabetes

Medical News: Kidney Disease Common in Undiagnosed and Prediabetes – in Nephrology, General Nephrology from MedPage Today

More than 40% of people with undiagnosed diabetes had chronic kidney disease, based on albuminuria or reduced estimated glomerular filtration rate (eGFR) — just as many as in those with diagnosed diabetes, according to Laura C. Plantinga, ScM, of San Francisco General Hospital and University of California San Francisco, and colleagues.

Notably, 56.2% of chronic kidney disease was stage 3 or 4 among those with prediabetes, indicated by a fasting plasma glucose between 100 and 126 mg/dl, and for whom kidney dysfunction was likely unsuspected.

CKD Risk and High HgbA1c

Arch Intern Med — Abstract: Poor Glycemic Control in Diabetes and the Risk of Incident Chronic Kidney Disease Even in the Absence of Albuminuria and Retinopathy: Atherosclerosis Risk in Communities (ARIC) Study, Dec 8/22, 2008, Bash et al. 168 (22): 2440

The more we know, the less we know.  The study population is small, but the findings merit our collective attention.  Think about these things the next time you are considering credits for the absence of retinopathy and/or albuminuria in a diabetic applicant.