Diet modifications (including more wine and cheese) May Help Reduce Cognitive Decline

Participants also answered questions about their food and alcohol consumption at baseline and through two follow-up assessments. The Food Frequency Questionnaire asked participants about their intake of fresh fruit, dried fruit, raw vegetables and salad, cooked vegetables, oily fish, lean fish, processed meat, poultry, beef, lamb, pork, cheese, bread, cereal, tea and coffee, beer and cider, red wine, white wine and Champaign and liquor.

Here are four of the most significant findings from the study:

Cheese, by far, was shown to be the most protective food against age-related cognitive problems, even late into life;

The daily consumption of alcohol, particularly red wine, was related to improvements in cognitive function;

Weekly consumption of lamb, but not other red meats, was shown to improve long-term cognitive prowess; and

Excessive consumption of salt is bad, but only individuals already at risk for Alzheimer’s Disease may need to watch their intake to avoid cognitive problems over time.

Iowa State University. “Diet modifications — including more wine and cheese — may help reduce cognitive decline, study suggests.” ScienceDaily. http://www.sciencedaily.com/releases/2020/12/201210145850.htm (accessed December 13, 2020).

Journal Reference

  1. Brandon S. Klinedinst, Scott T. Le, Brittany Larsen, Colleen Pappas, Nathan J. Hoth, Amy Pollpeter, Qian Wang, Yueying Wang, Shan Yu, Li Wang, Karin Allenspach, Jonathan P. Mochel, David A. Bennett, Auriel A. Willette. Genetic Factors of Alzheimer’s Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study. Journal of Alzheimer’s Disease, 2020; 78 (3): 1245 DOI: 10.3233/JAD-201058

Finally some good news.

Visceral fat delivers signal to the brain that hurts cognition

“We have identified a specific signal that is generated in visceral fat, released into the blood that gets through the blood brain barrier and into the brain where it activates microglia and impairs cognition.”

Visceral fat delivers signal to the brain that hurts cognition

Quote and article link presented without the usual sarcasm.

Molecule found in oranges could reduce obesity and prevent heart disease and diabetes

In mice, so don’t start gorging on oranges.

Sorry, sarcasm restriction didn’t last long.

Early studies on the diet suggested red wine was a major contributor to the health benefits of the Mediterranean diet because it contains a compound called resveratrol, which activated a certain pathway in cells known to increase lifespan and prevent aging-related diseases. However, work in Mashek’s lab suggests that it is the fat in olive oil, another component of the Mediterranean diet, that is actually activating this pathway.

Olive oil in the diet may also help mitigate aging-related diseases

 

Medical News: Diabetes May Speed Cognitive Decline – in Neurology, General Neurology from MedPage Today

Over 9 years, those who had diabetes had significantly worse cognitive decline on two separate tests compared with those who didn’t have the disease (P=0.008 and P=0.001), Kristine Yaffe, MD, of the University of California San Francisco, and colleagues reported online in the Archives of Neurology.

via Medical News: Diabetes May Speed Cognitive Decline – in Neurology, General Neurology from MedPage Today.

Berry Good News

In the current analysis, Elizabeth Devore, an instructor in medicine at Brigham and Women’s Hospital, and her colleagues addressed the gap in the research by reviewing the eating habits of a single cohort of 16,000 women participating in the Nurses Health Study. During their 50s and 60s, every four years the women answered questions by phone about what they ate. And in their 70s, they came into the lab for six different cognitive function tests. Devore and her team also had information on the women’s education, income and other socioeconomic factors that can affect cognitive function.

 

She and her colleagues focused their attention on berries because rodent studies showed that the key compound in berries, a flavonoid called anthocyanidin, could seep through the blood and into brain tissues — specifically concentrating in the hippocampus, which is responsible for learning and memory. As an antioxidant, flavonoids also fight inflammation and oxidation, both processes that affect aging brain cells.

 

The Advantages of the Middle-Age Brain -TIME.com

A study in the British Medical Journal lit up the Internet last week with the conclusion that cognitive decline begins at age 45. While it’s true that some innate skills like memory and speed of reasoning fall off as we age, other aspects of intelligence related to learning and experience actually improve.

via Patricia Cohen: The Advantages of the Middle-Age Brain | TIME Ideas | TIME.com.

Positive proof the older brain improves with time.  I found an article on some positive aspects of the aging brain.

Now if I could only remember where I put my car keys…