Researchers in Connecticut have found that obstructive sleep apnea (OSA) in patients with atrial fibrillation (AF) appears to be an independent predictor of stroke.
OSA is independently associated with DN in type 2 diabetes. eGFR declined faster in patients with OSA. Nitrosative stress may provide a pathogenetic link between OSA and DN. Interventional studies assessing the impact of OSA treatment on DN are needed.
An estimated 20% to 50% of commercial drivers have sleep apnea. That high proportion may be in part due to the sedentary nature of long-haul trucking that contributes to obesity as a risk factor for sleep apnea, according to a statement from the American Academy of Sleep Medicine in support of federal legislation.
Presented without the usual caustic comment.
- Obstructive sleep apnea is associated with cardiovascular morbidity and mortality, particularly heart failure, a study found.
- The severity of obstructive sleep apnea was significantly associated with higher levels of high-sensitivity troponin, suggesting that subclinical myocardial injury may play a role in the association with risk of heart failure.
After adjustment for other risk factors, each 10% decrease in the lowest nocturnal oxygen saturation among adults undergoing a first-time polysomnogram for suspected sleep-disordered breathing was associated with a 14% greater risk of sudden cardiac death or resuscitated cardiac arrest (HR 1.14, 95% CI 1.01 to 1.27), according to Virend Somers, MD, PhD, of the Mayo Clinic in Rochester, Minn., and colleagues.
Sleep factors associated with a significantly greater likelihood of remaining free from sudden cardiac death or resuscitated cardiac arrest included an apnea-hypopnea index of less than 20 events per hour (HR 1.60, 95% CI 1.14-2.24), a mean nocturnal oxygen saturation of 93% or higher (HR 2.93, 95% CI 1.98-4.33), and a lowest nocturnal oxygen saturation of 78% or higher (HR 1.81, 95% CI 1.28-2.56), the researchers reported online in the Journal of the American College of Cardiology.
Yes. CPAP compliance matters.