The Prognostic Value of N-Terminal Pro–B-Type Natriuretic Peptide for Death and Cardiovascular Events in Healthy Normal and Stage A/B Heart Failure Subjects

Conclusions: The investigators concluded that these findings do not support the use of NT-proBNP as a cardiovascular biomarker in healthy normal subjects, and have important implications for NT-proBNP–based strategies for early detection and primary prevention of cardiovascular disease.