Lexiscan (regadenoson) and Adenoscan (adenosine): Drug Safety Communication – Rare but Serious Risk of Heart Attack and Death

BACKGROUND: Lexiscan and Adenoscan are FDA approved for use during cardiac nuclear stress tests in patients who cannot exercise adequately. Lexiscan and Adenoscan help identify coronary artery disease. They do this by dilating the arteries of the heart and increasing blood flow to help identify blocks or obstructions in the heart’s arteries. Lexiscan and Adenoscan cause blood to flow preferentially to the healthier, unblocked or unobstructed arteries, which can reduce blood flow in the obstructed artery. In some cases, this reduced blood flow can lead to a heart attack, which can be fatal. RECOMMENDATIONS: Screen all nuclear stress test candidates for their suitability to receive Lexiscan or Adenoscan. Avoid using these drugs in patients with signs or symptoms of unstable angina or cardiovascular instability, as these patients may be at greater risk for serious cardiovascular adverse reactions. Cardiac resuscitation equipment and trained staff should be available before administering Lexiscan or Adenoscan.

via Safety Alerts for Human Medical Products > Lexiscan regadenoson and Adenoscan adenosine: Drug Safety Communication – Rare but Serious Risk of Heart Attack and Death.

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READ THIS NOW – Writing Wednesdays: “Poof Goes the Middle Class”

People are becoming entrepreneurs. The mind-set of the employee is vanishing like the factory where it was born. It has to. We’ll all die if we wait for some force outside ourselves—business or government—to bring us jobs or teach us who we are or how we ought to live.

We have to invent our own ways, and that’s just what we’re doing.

via Writing Wednesdays: “Poof Goes the Middle Class”.

Poof goes the middle class – latimes.com.

A couple of weeks ago I caught up with my old college buddy on the phone.  I asked how his son was doing after taking refuge in his parents’ basement post college graduation.

“Michael’s doing great.  He moved out to Brooklyn and is doing project work.  Very happy, very busy.  Michael has four or five projects on the go.”

Call it what you want – freelancer, contract worker, portfolio careerist.  The employee mindset is becoming a thing of the past.

HbA1c and the Risks for All-Cause and Cardiovascular Mortality in the General Japanese Population

High HbA1c levels were associated with increased risk for all-cause mortality and death from CVD, coronary heart disease, and cerebral infarction in general East Asian populations, as in Western populations.

via HbA1c and the Risks for All-Cause and Cardiovascular Mortality in the General Japanese Population.