Culture

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“Find a niche. The more obscure the better. Be the only Tibetan yak milk importer in the country. Or craft the best hand-made shoes in Milan. OR be the guy you call when billionaires in Houston are divorcing their spouses of thirty years.”

Hugh MacLeod

Writing Wednesdays: “I’m On A Mission”

Writing Wednesdays: “I’m On A Mission”.

“The mission devours you, but it feeds you too. It endows you with focus. It lends your actions meaning. You define it and it defines you.

If you’re reading this blog, my guess is that you’re on a mission too. Don’t tell me. I don’t need to know what it is. I respect you just for having it. I salute you. If we pass in the street, I will see that mission in your eyes and I’ll silently honor it and honor you.

You had no choice in your mission, did you? You didn’t pick it. It picked you, just like it picked Jake and Elwood Blues.

That’s not bad company to be in.”

Steven Pressfield

Early metabolic acidosis and coma in massive acetaminophen overdose | The Poison Review

KEY TAKE-HOME POINT: Always remember to include APAP on the differential diagnosis of high-anion-gap metabolic acidosis. A good mnemonic is A CAT MUDPILE:

  • Aspirin
  • Cyanide, carbon monoxide
  • Acetaminophen
  • Theophylline
  • Methanol, metformin
  • Uremia
  • Diabetic ketoacidosis (or alcoholic ketoacidosis)
  • Propylene glycol
  • Iron, INH
  • Lactic acidosis
  • Ethyelene glycol

via Early metabolic acidosis and coma in massive acetaminophen overdose | The Poison Review.

This is simply a fun blog post.

High glycemic index diet as a risk factor for depression: analyses from the Women’s Health Initiative

High glycemic index diet as a risk factor for depression: analyses from the Women’s Health Initiative.

Results: We found a progressively higher dietary GI to be associated with increasing odds of incident depression in fully adjusted models (OR for the fifth compared with first quintile: 1.22; 95% CI: 1.09, 1.37), with the trend being statistically significant (P = 0.0032). Progressively higher consumption of dietary added sugars was also associated with increasing odds of incident depression (OR for the fifth compared with first quintile: 1.23; 95% CI: 1.07, 1.41; P-trend = 0.0029). Higher consumption of lactose, fiber, nonjuice fruit, and vegetables was significantly associated with lower odds of incident depression, and nonwhole/refined grain consumption was associated with increased odds of depression.