Fatigue and Higher Mortality

Glynn and her colleagues administered the Pittsburgh Fatigability Scale to 2,906 participants aged 60 or older in the Long Life Family Study, an international study that follows family members across two generations. Participants ranked from 0 to 5 how tired they thought or imagined that certain activities — such as a leisurely 30-minute walk, light housework or heavy gardening — would make them. Follow-up for this work concluded at the end of 2019, to avoid any increased mortality impact from the COVID-19 pandemic, which gave the team an average of 2.7 years of data on each participant. After accounting for a variety of factors that influence mortality, such as depression, pre-existing or underlying terminal illness, age and gender, the team found that participants who scored 25 points or higher on the Pittsburgh Fatigability Scale were 2.3 times more likely to die in the 2.7 years after completing the scale, compared to their counterparts who scored below 25.

University of Pittsburgh. “Feelings of fatigue predict early death in older adults.” ScienceDaily. http://www.sciencedaily.com/releases/2022/01/220124084616.htm (accessed January 27, 2022).

What Supply Chain Issues?

The App That Helps Me Be a More Patient Centered Physician — A Country Doctor Writes:

One of the most rewarding things I do in my clinic happens on my iPhone. When I sit down with a middle aged patient to talk about their cardiovascular risk, I open the risk calculator created by the American Heart Association and the American College of Cardiology. I talk my way through as I enter […]

The App That Helps Me Be a More Patient Centered Physician — A Country Doctor Writes:

The risk calculator is quite useful but I re-blogged this post for its link to the Hale study, which was news to me. This study published in 2004 showed older people between the ages of 70 and 90 who followed a Mediterranean diet have 50% lower rate of all-cause and cause-specific mortality than people who dine on the SAD Western diet. The four primary risk factors were diet, moderate alcohol intake, physical activity, and non-smoking.

Lifestyle matters.

Why Do They Call Chickenpox Chickenpox?

The Bubble Wrap Plus is a monthly paediatric journal club reading list from Anke Raaijmakers working with Professor Jaan Toelen & his team of the University Hospitals in Leuven. This comprehensive list of ‘articles to read’ comes from 34 journals, including Pediatrics, The Journal of Pediatrics, Archives of Disease in Childhood, JAMA Pediatrics, Journal of Paediatrics and Child Health, NEJM, and many more.

Anke Raaijmakers . Bubble Wrap PLUS – January 2022, Don’t Forget the Bubbles, 2022. Available at: https://doi.org/10.31440/DFTB.47066

Just one of the many interesting articles and studies you’ll find at this website. I’ve already earmarked a few for my weekend reading.

Exercise Alters Brain Chemistry – May Protect Aging Synapses

When elderly people stay active, their brains have more of a class of proteins that enhances the connections between neurons to maintain healthy cognition.

University of California – San Francisco. “Exercise alters brain chemistry to protect aging synapses: Enhanced nerve transmission seen in older adults who remained active.” ScienceDaily. http://www.sciencedaily.com/releases/2022/01/220107100955.htm (accessed January 8, 2022).

I was about to write a snarky comment but I forgot what it was.

Journal Reference – Kaitlin Casaletto, Alfredo Ramos‐Miguel, Anna VandeBunte, Molly Memel, Aron Buchman, David Bennett, William Honer. Late‐life physical activity relates to brain tissue synaptic integrity markers in older adults. Alzheimer’s & Dementia, 2022; DOI: 10.1002/alz.12530

A Patent-Free Covid Vaccine for the World

While Big Pharma corporations took billions of dollars in public funding to help develop vaccines from which they then reaped enormous profits while often charging exorbitant prices, Hotez and Battazzi created Cobervax with $7 million, mostly from private investors. One of these, Austin vodka distiller Tito’s, contributed $1 million to the effort.

Texas Team Applauded for Giving What Big Pharma Refuses: A Patent-Free Vaccine to the World — https://www.commondreams.org/news/2021/12/30/texas-team-applauded-giving-what-big-pharma-refuses-patent-free-vaccine-world

And for whatever reason everyone seems to be out of stock for an at home rapid Covid-19 antigen test.

If I drank vodka I would only buy Tito’s for the rest of my life.

Acute and Chronic Alcohol Consumption and the Risk of Atrial Fibrillation: What Did We Learn in 2021? — The Skeptical Cardiologist

As we approach the eve of the New Year, the skeptical cardiologist recognizes that many of you will be consuming vast quantities of alcohol tomorrow night. Whether this is done in celebration or in hopes of transiently forgetting pandemical stressors please be aware that as the fermented beverage of your choice begins to cloud your…

Acute and Chronic Alcohol Consumption and the Risk of Atrial Fibrillation: What Did We Learn in 2021? — The Skeptical Cardiologist

Thank you Dr. Pearson.