Published online before print February 16, 2016, DOI: 10.1200/JCO.2015.65.7759 Ronald C. Chen, R. Bryan Rumble, D. Andrew Loblaw, Antonio Finelli, Behfar Ehdaie, Matthew R. Cooperberg, Scott C. Morgan, Scott Tyldesley, John J. Haluschak, Winston Tan, Stewart Justman, and Suneil Jain
Cancer
Second Cancers Portend ‘Dismal Outcome’ in Myeloma | Medpage Today
Mortality risk more than doubles; AML especially ominous
Source: Second Cancers Portend ‘Dismal Outcome’ in Myeloma | Medpage Today
Incidence of Melanoma Doubled Over Last 30 Years — Physician’s First Watch
Vital Signs: Melanoma Incidence and Mortality Trends and Projections — United States, 1982–2030
Hodgkin Lymphoma Survivors Need Long-Term Follow-Up for CVD | Medpage Today
Hodgkin lymphoma (HL) survivors experience increased risks of cardiovascular disease (CVD) for as long as 40 years after initial HL treatment, according to a Dutch study published online in JAMA Internal Medicine on April 27, 2015.
Furthermore, compared with the general population, HL patients run four- to almost seven-fold increased risks of coronary heart disease (CHD) or cardiomyopathy/congestive heart failure (HF) 35 years or more after treatment, resulting in 857 excess CV events per 10,000 person-years. More than half of patients with a CVD will experience multiple CV events over time.
via Hodgkin Lymphoma Survivors Need Long-Term Follow-Up for CVD | Medpage Today.
Diet and Colon Cancer Risk – CBS News
Two-week diet swap shows impact on colon cancer risk – CBS News.
They found that only two weeks of diet exchange was enough change the makeup of the intestinal microbiota and affect a number of biomarkers associated with colon cancer risk. The rate of cell turnover in the intestinal lining, levels of fiber fermentation, bacterial metabolic activity, and inflammation all reflected the change in eating patterns.
American Institute for Cancer Research (AICR): CRU: Report: Obesity and 3 Daily Alcoholic Drinks Increase Liver Cancer Risk
The report also reaffirms the clear link between alcohol consumption and liver cancer, and for the first time quantifies the amount at which risk for liver cancer rises. “We now have a little more precision on the alcohol-liver cancer link,” said Hursting. “Getting above three drinks a day seems to dramatically impact the tumorigenic process and increase risk.”
More coffee! Less beer!
Melanoma Risk Appears Doubled in Airline Pilots, Cabin Crew — Physician’s First Watch
Melanoma Risk Appears Doubled in Airline Pilots, Cabin Crew — Physician’s First Watch.
Researchers analyzed data from 19 trials comprising over 250,000 participants. They found that pilots and cabin crew workers had roughly twice the risk for melanoma as the general population — a finding that held true for both men and women. Pilots and cabin crew members also had a 42% increased risk for melanoma mortality. – See more at: http://www.jwatch.org//fw109248/2014/09/04/melanoma-risk-appears-doubled-airline-pilots-cabin-crew#sthash.q9tTZsuy.dpuf
Viagra and Melanoma Risk
Viagra Frisky Might Be Melanoma Risky.
Men who used the erectile-function drug sildenafil (Viagra) had almost twice the risk of melanoma compared with men who never used the drug, a study of 26,000 men showed.
Recent sildenafil use was associated with an 84% greater risk of melanoma.
Sleep Apnea Linked to Cancer
Moderate-to-severe OSA was associated with a 2.5-fold higher likelihood of incident cancer (95% CI 1.2-5.0) after adjustment for obesity and a full range of other factors, Nathaniel Marshall, PhD, of the University of Sydney Nursing School in Australia, and colleagues found.
Cancer mortality was 3.4 times more common (95% CI 1.1-10.2) in those with sleep apnea than with no sleep apnea during 20 years of follow-up, they reported in the April 15 issue of theJournal of Clinical Sleep Medicine.
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