Heart Minute: Risk Factors for Aortic Stenosis

In mice.
BBC NEWS | Health | Low-carb diets ‘damage arteries’
The low-carb diet did not affect cholesterol levels, but there was a significant difference on the impact on atherosclerosis – the build-up of fatty plaque deposits in the arteries that can lead to heart attacks or strokes.
After 12 weeks, the mice eating the low-carb diet had gained less weight, but developed 15% more atherosclerosis than those on the standard mice food. For the western diet group there was 9% more atherosclerosis.

Here is a pretty good article on NT-proBNP.
Read it after you watch the video on giant killer squids.

To look farther down the disease spectrum than the analysis in ACCORD, Dr. Aguilar’s group retrospectively examined outcomes for a national cohort of 5,815 ambulatory diabetic patients with established heart failure who were treated in ambulatory clinics at VA medical centers.
During two years of follow-up, mortality rates were:
* 25.0% in the bottom quintile with hemoglobin A1c levels of 6.4% or less.
* 23.0% in the group with A1c levels of 6.5% to 7.1%.
* 17.7% in the middle quintile with glycosylated hemoglobin levels above 7.1% but no more than 7.8%.
* 22.5% in the group with A1c levels of 7.9% to 9.0%.
* 23.2% in the top quartile with hemoglobin A1c levels above 9.0%.
This is must-have information for all the life settlement underwriters out there.

Lipoprotein-Associated Phospholipase A2 a Novel Risk Marker
Hey Hank! Give us a speech on this biomarker!
CONCLUSIONS The presence of diabetes was associated with a threefold higher CVD mortality risk, and metabolic syndrome status did not modify this risk. Our findings support the fact that physicians should be aggressive in using CVD risk–reducing therapies in all diabetic patients regardless of metabolic syndrome status.
Please tell me you already knew this…