MKSAP: 22-year-old man with T1DM

Key Point  -Because factors such as fever and exercise can cause a transient increase in protein excretion, patients with type 1 diabetes mellitus who have abnormal findings on annual measurement of the urine albumin excretion should undergo repeat urinalyses twice within the next 6 months; positive findings on two of the three urine samples would confirm a diagnosis of microalbuminuria defined as a urine albumin-creatinine ratio between 30 and 300 mg/g.

via MKSAP: 22-year-old man with type 1 diabetes mellitus.

DM Risk – White Rice Bad

Eating more white rice may up the risk of type 2 diabetes, especially for Asian populations, researchers said.Patients who ate the greatest amounts of the grain had a 27% greater risk of developing the disease than those who ate the least, and the relative risk was higher among Asian patients, Qi Sun, PhD, of Harvard, and colleagues, reported in BMJ.

via Medical News:Diabetes Risk: White Rice Joins White Bread – in Primary Care, Diabetes from MedPage Today.

This is very bad news for Chinese take out businesses.

Mortality Risk Quantified for Diabetes Plus Kidney Disease

This meta-analysis found that the presence of chronic kidney disease strongly predicted mortality risk in patients with type 2 diabetes. Chronic kidney disease more than doubles mortality risk in patients with type 2 diabetes, researchers found. In an analysis of nearly two dozen randomized controlled trials involving diabetic patients, the highest mortality rates were observed in those trials that required the inclusion of patients with renal disease, according to Marc Pfeffer, MD, PhD, of Brigham and Women’s Hospital in Boston, and colleagues. Trials that selected for patients with elevated serum creatinine or impaired estimated glomerular filtration rate eGFR had mortality rates of 5.9 to 8.2 per 100 patient-years, whereas the rest of the trials had rates no higher than 3.3, the researchers reported online in the Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease.

via Medical News:Mortality Risk Quantified for Diabetes Plus Kidney Disease – in Cardiovascular, Diabetes from MedPage Today.

FDA Adds Diabetes Warning to Statin Labels

The diabetes warning has been rumored as a possibility since the findings from the JUPITER trial of rosuvastatin revealed an unexpected 27% increase in new onset diabetes among patients randomized to the statin.That finding was especially perplexing because JUPITER was a study of statins in patients who had no history of cardiovascular disease, the so-called healthy patient trial. Moreover, based on the JUPITER results, the FDA approved rosuvastatin for primary prevention.The FDA said hyperglycemia was also observed among patients treated with 40-mg atorvastatin in a substudy of PROVE-IT TIMI 22, and a meta-analysis of data from 13 statin trials “reported that statin therapy was associated with a 9% increased risk for incident diabetes.”

via Medical News:FDA Adds Diabetes Warning to Statin Label – in Cardiovascular, Dyslipidemia from MedPage Today.

Gender Differences in Diabetes

How Diabetes Differs for Men and Women | Diabetes Forecast Magazine

Women with diabetes have it worse, on average, than men with diabetes. This shocking inequality was revealed in a 2007 study that found that, between 1971 and 2000, death rates fell for men with diabetes, while rates for women with the disease didn’t budge. Plus, while men with diabetes live 7.5 years less on average than those who don’t have the disease, among women the difference is even greater: 8.2 years.