Blood Pressure and Complications in DM2 and no Previous CVD – The BMJ

August 6, 2016August 6, 2016 / SupremeCmdr / Leave a comment

Conclusions: Lower systolic blood pressure than currently recommended is associated with significantly lower risk of cardiovascular events in patients with type 2 diabetes. The association between low blood pressure and increased mortality could be due to concomitant disease rather than anti-hypertensive treatment.

Source: Blood pressure and complications in individuals with type 2 diabetes and no previous cardiovascular disease: national population based cohort study | The BMJ

Diabetes treatments and risk of heart failure, cardiovascular disease, and all cause mortality: cohort study in primary care – The BMJ

July 23, 2016July 23, 2016 / SupremeCmdr / Leave a comment

Conclusions – There are clinically important differences in risk of cardiovascular disease, heart failure, and all cause mortality between different diabetes drugs alone and in combination. Overall, use of gliptins or glitazones was associated with decreased risks of heart failure, cardiovascular disease, and all cause mortality compared with non-use of these drugs. These results, which do not account for levels of adherence or dosage information and which are subject to confounding by indication, might have implications for prescribing of diabetes drugs.

Source: Diabetes treatments and risk of heart failure, cardiovascular disease, and all cause mortality: cohort study in primary care | The BMJ

Recurrent Diabetic Ketoacidosis Raises Mortality Risk in T1D – Medpage Today

July 11, 2016July 11, 2016 / SupremeCmdr / Leave a comment

Recurrent episodes of diabetic ketoacidosis (DKA) were associated with a substantially increased risk of death in patients with type 1 diabetes, according to a retrospective single-center Scottish study.

Limitations of the study included its single-center design, which “does leave the generalizability of these results open to question,” Gibb and colleagues said.

Source: Recurrent Diabetic Ketoacidosis Raises Mortality Risk in T1D | Medpage Today

HbA1c Racial Differences Complicate Diagnosis

July 3, 2016July 3, 2016 / SupremeCmdr / Leave a comment

Blacks generally have higher HbA1c levels than whites. Rates among Hispanics and Asians also tend to be higher than in whites, although the discrepancy has not been as well-studied in these groups, says University of Cincinnati professor of medicine Robert M. Cohen, MD.

Source: HbA1c Racial Differences Complicate Diagnosis

Type 2 Diabetes Remission Rates After Laparoscopic Gastric Bypass and Gastric Banding: Results of the Longitudinal Assessment of Bariatric Surgery Study | Diabetes Care

June 22, 2016June 22, 2016 / SupremeCmdr / Leave a comment

CONCLUSIONS – Diabetes remission up to 3 years after RYGBP and LAGB was proportionally higher with increasing postsurgical weight loss. However, the nearly twofold greater weight loss–adjusted likelihood of diabetes remission in subjects undergoing RYGBP than LAGB suggests unique mechanisms contributing to improved glucose metabolism beyond weight loss after RYGBP.

Source: Type 2 Diabetes Remission Rates After Laparoscopic Gastric Bypass and Gastric Banding: Results of the Longitudinal Assessment of Bariatric Surgery Study | Diabetes Care

Type 2 Diabetes Rates Quadruple Worldwide Since 1980

April 15, 2016April 15, 2016 / SupremeCmdr / Leave a comment

The American Samoa Story

Of the Pacific Island nations, American Samoa had the highest national prevalence of diabetes in 2014, with over 30% of Samoan men and women affected, and the country is also the one where women have the highest mean body mass index (BMI) in the world, notes Stephen McGarvey, PhD, of Brown University, Providence, Rhode Island, an anthropologist with extensive research experience on Samoa, who contributed to both the Lancet papers on diabetes and obesity.

“The Samoans started early and went to very high levels…but there are some other nations, or even parts of nations, whose rate of change recently has [also] been very rapid,” Dr McGarvey observes in a press release from his institution.

Dr McGarvey cites the “nutrition transition” — a move away from traditional diet to a more Westernized diet characterized by high-calorie, high-fat processed and prepared foods — as playing a large role in what has happened in American Samoa and elsewhere in the developing world.

Also, modernization has meant travel by car and bus has replaced walking, and work has become less physically demanding and more sedentary, he adds.

Source: Type 2 Diabetes Rates Quadruple Worldwide Since 1980