Thursday 08.12.21 – More Diabetes Research for Your Reading Pleasure

Prevalence and incidence of microvascular and macrovascular complications over 15 years among patients with incident type 2 diabetes

Our findings show that a substantial proportion of patients had existing complications including CKD, stable angina, and peripheral neuropathy at the time of T2D diagnosis. Results also show that among those newly diagnosed with T2D, the highest incidence rates of complications included peripheral neuropathy, CKD, and CVD (myocardial infarction, unstable angina, and stroke).

Time to incidence of microvascular and macrovascular complications was only a few years; peripheral vascular disease, stable angina, CKD, and peripheral neuropathy developed earlier in the disease course.

BMJ Open Diabetes Research and Care – http://dx.doi.org/10.1136/bmjdrc-2020-001847

Diabetic Ketoacidosis and Mortality in People With Type 1 Diabetes and Eating Disorders

CONCLUSIONS Adolescents and young adults with type 1 diabetes and eating disorders have more than triple the risk of DKA and nearly sixfold increased risk of death compared with their peers without eating disorders.

Diabetes Care 2021 Aug; 44(8): 1783-1787. https://doi.org/10.2337/dc21-0517

Fenofibrate Use Is Associated With Lower Mortality and Fewer Cardiovascular Events in Patients With Diabetes: Results of 10,114 Patients From the Korean National Health Insurance Service Cohort

Diabetes Care 2021 Aug; 44(8): 1868-1876. https://doi.org/10.2337/dc20-1533

I’ve been out of town the past three weekends in a row. Prior to taking these trips I was feeling a bit burned out. I had little desire to continue my research activities. I had even less desire to write or post to my blogs. But as suddenly as my energy levels dipped, the mojo came back.

Hiatus is over. The SupremeCmdr is back.

Just Another Sweet Saturday Morning

These findings show that the prevalence of food insecurity in the U.S. is highest among Americans for whom a healthy diet is especially critical—Medicaid enrollees with insulin-dependent diabetes and diabetes-related eye or kidney complications (over 40% were food insecure). The problem of co-occurring food insecurity and diabetes among the nation’s disadvantaged has likely worsened during the coronavirus disease 2019 pandemic.

The Prevalence of Food Insecurity Is Highest Among Americans for Whom Diet Is Most Critical to Health — Diabetes Care 2021 Jun; 44(6): e131-e132. https://doi.org/10.2337/dc20-3116

In patients with newly diagnosed T2DM, alcohol abstinence was associated with a low risk of AF development. Lifestyle modifications, such as alcohol abstinence, in patients newly diagnosed with T2DM should be recommended to reduce the risk of AF.

Diabetes Care 2021 Jun; 44(6): 1393-1401. https://doi.org/10.2337/dc20-2607

New research published in Diabetologia has shown that if people achieve and maintain substantial weight loss to manage their type 2 diabetes, many can also effectively control their high blood pressure and stop or cut down on their anti-hypertensive medication.

Diabetologia. “Diabetes remission diet also lowers blood pressure and reduces need for medication.” ScienceDaily. ScienceDaily, 31 May 2021 — https://www.sciencedaily.com/releases/2021/05/210531180422.htm

Sat 6/19

Spice Blend

1 teaspoon ground cumin
1 teaspoon ground coriander
1 teaspoon smoked paprika
½ teaspoon ground turmeric
½ teaspoon dried oregano
½ teaspoon dried chili flakes
¼ teaspoon ground cinnamon

Copied from The First Mess Seven Spice Chickpea Stew recipe https://thefirstmess.com/2016/01/20/vegan-seven-spice-chickpea-stew-recipe/ so I don’t have to look it up online again if I decide to make this dish tonight.

During Pandemic Year One I lost 25 pounds. My PCP was impressed but when I told her how my diet changed she put her “doctor face” on, looked me straight in the eyes and said,

“I can’t wait to see your blood test results.”

Due to my family history my risk of developing DM2 is approximately 25% higher than the average underwriter. When I asked a prominent Endocrinologist for some advice many years ago he too put on his “doctor face” looked me straight in the eyes and said,

“Stay as thin as you can as long as you can.”

Yesterday I went to see Kevin and got a fresh flattop. The first question he asked was,

“Did you lose more weight?”

No, I haven’t. But my face definitely looks thinner without a mask.

BTW my blood work was about the same as last year even with my change in diet.

Preferred Plus NN.

The Latest in COVID-19 News: Week Ending 04.24.21 – NEJM Journal Watch

Click on the link for the NEJM Journal Watch weekly update.  Not a lot of links this week for SARS-CoV-2 articles but again I did not forget to post this.

https://www.jwatch.org/fw117733/2021/04/24/covid-19-news-week-ending-apr-24-2021

So in the spirit of big news that didn’t get mentioned in this week’s NEJM Journal Watch:

FDA, CDC Lift Suspension of Johnson & Johnson Vaccine

Cite this: FDA, CDC Lift Suspension of Johnson & Johnson Vaccine – Medscape – Apr 23, 2021 — https://www.medscape.com/viewarticle/949913

Meanwhile pray for India.

India has recorded nearly a million infections in three days, with 346,786 new cases overnight into Saturday.

India Covid surge: Hospitals send SOS as record deaths registered — https://www.bbc.com/news/world-asia-56870410

The Latest in COVID-19 News: Week Ending 04.17.21 – NEJM Journal Watch

Click on the link for the NEJM Journal Watch weekly update.  A blood clot week for SARS-CoV-2 articles.

https://www.jwatch.org/fw117711/2021/04/17/covid-19-news-week-ending-apr-17-2021

A team of researchers in the United Kingdom conducted an in-depth investigation of 22 patients who developed serious blood clots combined with a drop in blood platelets after receiving a dose of the AstraZeneca vaccine, which is now called Vaxzevria. They also tested an additional patient who had clinical signs of a drop in blood platelets after vaccination. Nearly all the patients — 22 of 23 — tested positive for unusual antibodies to platelet factor 4, a signaling protein that helps the body coordinate blood clotting.

Citation: Researchers Detail More Cases of Rare Clots Tied to COVID Vaccines – Medscape – Apr 16, 2021 — https://www.medscape.com/viewarticle/949473?src=rss

The Latest in COVID-19 News: Week Ending 04.10.21 – NEJM Journal Watch

Click on the link for the NEJM Journal Watch weekly update.  Another good week for SARS-CoV-2 articles. For the second week in a row I did not forget to post this link.

https://www.jwatch.org/fw117693/2021/04/10/latest-covid-19-news-week-ending-apr-10

Meanwhile in B.C. Canada…

B.C. shatters records with 1,293 new COVID-19 cases, pushing average over 1,000 per day — https://globalnews.ca/news/7746859/b-c-shatters-records-with-1293-new-covid-19-cases-pushing-average-over-1000-a-day/

The Latest in COVID-19 News: Week Ending 03.20.21 – NEJM Journal Watch

Click on the link for the NEJM Journal Watch weekly update.  Another good week for SARS-CoV-2 articles. Sorry about not posting last week’s Journal Watch link of links. I forgot AND I was out of town which made me forget.

https://www.jwatch.org/fw117630/2021/03/20/latest-covid-19-news-week-ending-mar-20-2021

Meanwhile Sammy sings from what appears to be an empty closet.

The Latest in COVID-19 News: Week Ending 02.27.21 – NEJM Journal Watch

Click on the link for the NEJM Journal Watch weekly update.  One hell of a great week for SARS-CoV-2 articles.

https://www.jwatch.org/fw117559/2021/02/27/latest-covid-19-news-week-ending-feb-27-2021

Meanwhile at the NIH/NIC…

People who have had evidence of a prior infection with SARS-CoV-2, the virus that causes COVID-19, appear to be well protected against being reinfected with the virus, at least for a few months, according to a newly published study from the National Cancer Institute (NCI).

NIH study finds that people with SARS-CoV-2 antibodies may have a low risk of future infection – https://www.nih.gov/news-events/news-releases/nih-study-finds-people-sars-cov-2-antibodies-may-have-low-risk-future-infection