Association of Clinical Symptomatic Hypoglycemia With Cardiovascular Events and Total Mortality in Type 2 Diabetes

CONCLUSIONS: Symptomatic hypoglycemia, whether clinically mild or severe, is associated with an increased risk of cardiovascular events, all-cause hospitalization, and all-cause mortality. More attention may be needed for diabetic patients with hypoglycemic episodes.

via Association of Clinical Symptomatic Hypoglycemia With Cardiovascular Events and Total Mortality in Type 2 Diabetes.

Watch those hypoglycemic episodes in applicants with T2DM.

Association Between BMI Measured Within a Year After Diagnosis of Type 2 Diabetes and Mortality

CONCLUSIONS: Patients categorized as normal weight or obese with T2DM within a year of diagnosis of T2DM exhibit variably higher mortality outcomes compared with the overweight group, confirming a U-shaped association of BMI with mortality. Whether weight loss interventions reduce mortality in all T2DM patients requires study.

via Association Between BMI Measured Within a Year After Diagnosis of Type 2 Diabetes and Mortality.

Could we have another U shaped mortality curve?  Watch that BMI.

Medical Apps – Tipping Point?

There are cheap dongles that can do sonograms good enough for office use, sensors and apps that can do blood tests, sweat tests and other chemical diagnostics. One type of pill has been developed that reports when the patient has swallowed it. When the pill encounters stomach acids, it sends out a tiny electronic pulse. The pulse is picked up by a small adhesive patch the patient wears on his or her abdomen. The patch, in turn, detects when the patient’s smart phone is on and close by, and sends out a Bluetooth signal. An app on the phone picks up the Bluetooth signal and sends an instant message to the clinician who is tracking the use of the drug.

via Medical apps: We are approaching the tipping point.

Interesting article.

Diastolic Dysfunction Common in RA

Patients with rheumatoid arthritis (RA) have an increased incidence of diastolic dysfunction, which may further raise their already high risk for congestive heart failure, a meta-analysis suggested.

 

Patients with RA have double the incidence of heart failure compared with the larger population, and this finding has prompted interest in determining the origins of heart failure in these patients.

via Diastolic Dysfunction Common in RA.

Azithromycin (Zithromax or Zmax) – Risk of Potentially Fatal Heart Rhythms

ISSUE: FDA is warning the public that azithromycin (Zithromax or Zmax) can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart rhythm. Patients at particular risk for developing this condition include those with known risk factors such as existing QT interval prolongation, low blood levels of potassium or magnesium, a slower than normal heart rate, or use of certain drugs used to treat abnormal heart rhythms, or arrhythmias. FDA has issued a Drug Safety Communication today as a result of our review of a study by medical researchers as well as another study by a manufacturer of the drug that assessed the potential for azithromycin to cause abnormal changes in the electrical activity of the heart.

via Safety Alerts for Human Medical Products > Azithromycin (Zithromax or Zmax): Drug Safety Communication – Risk of Potentially Fatal Heart Rhythms.