Medical News
Prostate Cancer Biomarker
The results, published in the Public Library of Science (PLoS) ONE journal, showed that MSMB is found at significantly lower levels in the urine of men diagnosed with prostate cancer than those without the disease. They also showed men with aggressive tumors were also likely to have lower levels of the protein in their urine.
Lehman’s Blog 10.11.2010
BMJ Group blogs: BMJ » Blog Archive » Richard Lehman’s journal review – 11 October 2010
Most medical research is clinically useless, and so, sadly, are most systematic reviews and meta-analyses.
The quote is from Lehman, not me.
Lehman’s Journal Review 10.4.2010
BMJ Group blogs: BMJ » Blog Archive » Richard Lehman’s journal review, 4 October 2010
Like about 40% of adults of my age in Western countries, I have a fatty liver, though I don’t qualify for having nonalcoholic fatty liver disease because I drink too much. If I wanted to know what is really happening to my liver I would have to have serial biopsies, as would several million people in the UK. This non-disease correlates with a number of other non-diseases such as asymptomatic reduced left systolic ejection fraction and pre-diabetes, and some real risk factors such as actual diabetes and high blood pressure. So I might die of vascular disease; or liver failure if I really overdo the wine; or else from cancer or general crumble or whatever else awaits me and everyone else. This paper on the risk of cardiovascular disease in patients with nonalcoholic fatty liver disease goes through the data and leaves me none the wiser: and by the way, these people are not patients and they don’t have a disease.
General crumble?
Low Carb Diets and Mortality
Low-Carbohydrate Diets and All-Cause and Cause-Specific Mortality — Ann Intern Med
Conclusion: A low-carbohydrate diet based on animal sources was associated with higher all-cause mortality in both men and women, whereas a vegetable-based low-carbohydrate diet was associated with lower all-cause and cardiovascular disease mortality rates.
Hypoglycemia in DM2 = Higher Mortality Risk
Type 2 diabetes patients who experienced these serious drops in blood glucose had nearly three times the risk of death and twice the risk of a major macrovascular event compared with those who didn’t experience hypoglycemia, Sophia Zoungas, MD, PhD, of the University of Sydney in Australia, and colleagues reported in the New England Journal of Medicine.
More on Vitamin D and Mortality (Old Guys Need to Read This)
Memantine for PDD or DLB
Underwriting Quick Notes:
- PDD = Parkinson’s Disease Dementia
- DLB = Dementia with Lewy Bodies
- Memantine = Namenda
Memantine seems to improve global clinical status and behavioural symptoms of patients with mild to moderate DLB, and might be an option for treatment of these patients.
Drink More Water
U.S. Kids Drink Too Little Water: Study
The results of this study should not be surprising.
Emphysema on CT Significantly Correlated With Mortality
Click through for the abstract. There is a link on the page for a PDF version.
CT Scan Findings of Emphysema Predict Mortality in COPD — CHEST
Results: Of the 251 patients, 79 died, with 40 classified as respiratory deaths not involving lung cancer. Univariate Cox analysis revealed that emphysematous change as assessed by CT scan, lung function, age, or BMI were significantly correlated with mortality. Multivariate analysis revealed that emphysematous change as assessed by CT scan had the best association with mortality.
Conclusions: Emphysematous change as assessed by CT scan predicts respiratory mortality in outpatients with various stages of COPD.
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