Five Lessons From the Niacin Failure.
Niacin With Statins? No Dice..
HPS2-THRIVE: As Niacin Fails, HDL’s Role Is Debated Anew.
Enjoy these articles. Taking niacin? Well…
Medical News
Emergency Medicine News – THC Dosing of Edible Marijuana in Colorado is Insane.
Avoid couchlock! Four things to know about cannabis pharmacology | The Poison Review.
Recently, the New York Times’ Pulitzer Prize-winning columnist Maureen Dowd got into trouble in Denver when she overdosed on a cannabis candy bar and experienced 8 hours of paranoia and couchlock.
Toxicology Rounds: Four Things Maureen Dowd Should Have Know… : Emergency Medicine News.
THC dosing of edible marijuana in Colorado is insane. Richard Zane, MD, the chairman of emergency medicine at the University of Colorado Medical Center in Denver, said on the National Public Radio talk show On Point that the amount of THC in some marijuana edibles is completely irrational. The usual recommended moderate starting dose is approximately 10 mg THC, and some cookies can contain six doses and some lollipops as many as 10. Dr. Zane said the university’s ED sees out-of-state marijuana tourists every day who present with bad reactions to THC, such as agitation, unremitting violent vomiting, hallucinations, and psychosis.
And finally, a link to Maureen Dowd’s column.
Don’t Harsh Our Mellow, Dude – NYTimes.com.
In March, a 19-year-old Wyoming college student jumped off a Denver hotel balcony after eating a pot cookie with 65 milligrams of THC. In April, a Denver man ate pot-infused Karma Kandy and began talking like it was the end of the world, scaring his wife and three kids. Then he retrieved a handgun from a safe and killed his wife while she was on the phone with an emergency dispatcher.
Diet Soda May Alter Our Gut Microbes And Raise The Risk Of Diabetes : The Salt : NPR
Now, a new study published in the journal Nature introduces a new idea: Diet sodas may alter our gut microbes in a way that increases the risk of metabolic diseases such as Type 2 diabetes — at least in some of us.
In the paper, researchers at the Weizmann Institute of Science in Israel describe what happened when they fed zero-calorie sweeteners, including saccharin, aspartame and sucralose, to mice.
“To our surprise, [the mice] developed glucose intolerance,” Weizmann researcher Eran Elinav tells us.
Diet Soda May Alter Our Gut Microbes And Raise The Risk Of Diabetes : The Salt : NPR.
Increases in Liver Injury Related to Herbal and Dietary Supplements — Physician’s First Watch
Researchers analyzed registry data from some 800 patients with liver injury either from medications excluding acetaminophen or herbal and dietary supplements. In the first 2 years of the registry, 7% of cases were due to herbal and dietary supplements, a proportion that increased to 20% a decade later. Hepatotoxicity from non-bodybuilding-related supplements required liver transplantation more often than injury from conventional drugs 13% vs. 3%; there were no cases of liver transplantation associated with bodybuilding supplements.
via Increases in Liver Injury Related to Herbal and Dietary Supplements — Physician’s First Watch.
Melanoma Risk Appears Doubled in Airline Pilots, Cabin Crew — Physician’s First Watch
Melanoma Risk Appears Doubled in Airline Pilots, Cabin Crew — Physician’s First Watch.
Researchers analyzed data from 19 trials comprising over 250,000 participants. They found that pilots and cabin crew workers had roughly twice the risk for melanoma as the general population — a finding that held true for both men and women. Pilots and cabin crew members also had a 42% increased risk for melanoma mortality. – See more at: http://www.jwatch.org//fw109248/2014/09/04/melanoma-risk-appears-doubled-airline-pilots-cabin-crew#sthash.q9tTZsuy.dpuf
In Bariatric Surgery, Sleeve Gastrectomy Now More Common than Bypass — Physician’s First Watch
In Bariatric Surgery, Sleeve Gastrectomy Now More Common than Bypass — Physician’s First Watch.
The authors examined data on some 44,000 patients undergoing surgery in a 39-hospital Michigan collaborative. From 2008 to 2013, the prevalence of sleeve gastrectomy rose from about 6% to 67% of bariatric procedures. The Roux-en-Y approach dropped from 58% to 27%; adjustable banding fell from 35% to 5%. – See more at: http://www.jwatch.org//fw109242/2014/09/03/bariatric-surgery-sleeve-gastrectomy-now-more-common#sthash.4m9BIpud.dpuf
Ebola Doctor Reveals How Infected Americans Were Cured – Scientific American
More Docs Wonder If Statins Are Worth the Risks
ED Visits for Drug-Related Suicide Attempts Double
Many Meds Taken by Seniors Can Raise Risk of Falls
Many Meds Taken by Seniors Can Raise Risk of Falls.
After adjusting for the number of medications a person was taking, the researchers found men and women taking opioid painkillers as well as men taking antidepressants were more than twice as likely to have a fall injury as seniors who were not taking those drugs. Women taking antidepressants were 75% more likely to have a fall injury.
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