Olanzapine – Think Bipolar and Schizophrenia

Medical News: FDA Okays Generic Version of Zyprexa – in Psychiatry, Schizophrenia from MedPage Today

The FDA has approved a generic version of atypical antipsychotic drug olanzapine (Zyprexa) to treat schizophrenia and bipolar disorder.

According to the AP story:

Drugs like Zyprexa can cost up to $500 per month. Generic versions can cut the cost by up to 80 percent.

This is great news.

Lower Cognitive Scores – Low B12?

Medical News: Brain Takes Multiple Hits from Low B12 Levels – in Neurology, General Neurology from MedPage Today

Markers of B12 insufficiency all predicted lower global cognitive scores over nearly five years of follow-up, Christine C. Tangney, PhD, of Rush University Medical Center in Chicago, and colleagues found.

Be Still…(it may help your brain)

Mindfulness Meditation Is Associated With Structural Changes in the Brain [NCCAM Research Results]

Brain images in the meditation group revealed increases in gray matter concentration in the left hippocampus. The hippocampus is an area of the brain involved in learning, memory, and emotional control, and is suspected of playing a role in producing some of the positive effects of meditation. Gray matter also increased in four other brain regions (though not in the insula, a region that has shown changes in other meditation studies) in the meditation group. Responses to the questionnaire indicated improvements in three of the five aspects of mindfulness in the mediators, but not the control group. 

The researchers concluded that these findings may represent an underlying brain mechanism associated with mindfulness-based improvements in mental health. Additional studies are needed to determine the associations between specific types of brain change and behavioral mechanisms thought to improve a variety of disorders.

Marijuana and Psychosis – Possible Link

 

Pot Use in Youth Ups Risk of Psychotic Symptoms in Later Life

The new findings are based on data on about 2,000 individuals in Germany who were 14 to 24 years old when they enrolled in the study, and who were then followed for 10 years. 

None of the participants had ever tried marijuana before entering the study, nor had any experienced psychotic symptoms.

The researchers found that those who started smoking pot during the 10 years of the trial had double the risk of developing psychotic symptoms such as hallucinations, even after adjusting for factors such as age, sex, socioeconomic status, other drug use and other psychiatric diagnoses.

And the more persistent the use, the more persistent the symptoms.

Chandler police link beheading to theft of marijuana from Mexican cartel – East Valley Tribune: Cop Shop

Depression + CHD = Bad

Medical News: Depression Plus Heart Disease Equal Lethal Combo – in Psychiatry, Depression from MedPage Today

The risk of all-cause mortality was elevated 67% for patients with coronary heart disease (P<0.05) and 2.10 times for those with depressive symptoms (P<0.001) in the long-running Whitehall II study of British civil servants.

But patients who had both conditions had a nearly five-fold risk compared with those who had neither (hazard ratio 4.99, P<0.001), Hermann Nabi, PhD, of the University of Versailles, France, and colleagues reported online in Heart.