Go to the following link for a list of SGLT2 Inhibitors.
An Update on SGLT2 Inhibitors for the Treatment of Diabetes Mellitus
Fournier Gangrene does not sound like a pleasant disease.
Go to the following link for a list of SGLT2 Inhibitors.
An Update on SGLT2 Inhibitors for the Treatment of Diabetes Mellitus
Fournier Gangrene does not sound like a pleasant disease.
The potential benefits and risks of cannabis
The information in this post first appeared in the March 2019 issue of Nutrition Action Healthletter.
Nice article summarizing the medical evidence for cannabis health benefits.

Cannabis Plus Opioids in Chronic Pain: Not a Great Combo
Previous research by Humphreys and colleagues showed that people who used medical cannabis also had higher rates of opioid use and misuse. “This is one of many examples where claims about the benefits of medical cannabis are not supported by evidence,” Humphreys told MedPage Today. The current study had several limitations: it relied on cross-sectional, self-reported data and was subject to possible selection bias and confounding. It also did not assess the frequency or quantity of cannabis or opioid use, or the type of chronic pain.
CONCLUSIONS – Metformin reduces the development of diabetes over 15 years. The subsets that benefitted the most include subjects with higher baseline fasting glucose or HbA1c and women with a history of GDM.
You can access the abstract and full study online at this link to the Diabetes Journal.
The commentary article at this link is also an interesting read.
Among veterans enrolled in VA and Part D, dual use of opioid prescriptions was independently associated with death from prescription opioid overdose. This risk factor for fatal overdose among veterans underscores the importance of care coordination across health care systems to improve opioid prescribing safety.
Full abstract at this link.
Read a quick history lesson here.
Read about psychosis risk here.
Pass the doobie please.
Regardless of the century, physicians throughout the ages have known that real medicines carry risks. Any truly medicinal substance is able to give a little whack to one or more bodily processes. The goal is to whack the body back into normal functioning. That’s basically what medicine is all about – strategically whacking our physiology. But anything capable of whacking (which is to say any real medicine) is capable of harming at least a few of the many patients who would take it. This fact is so non-negotiable that we have a name for doctors who claim to have discovered effective medicines that don’t have any risks: we call them quacks.
When Michelle Fenner signed up to run this year’s Los Angeles Marathon, it got her thinking: Tijuana, Mexico, is only a 2½-hour drive from L.A. Why not take a trip across the border and buy some insulin for her son? “It’s so easy to just go across the border,” mused Fenner. This idea had been…
via Americans Cross Border Into Mexico To Buy Insulin At A Fraction Of U.S. Cost — Kaiser Health News
In China Rx, Gibson and Singh discuss China’s long-term strategy to destroy the markets of Western countries in China and take over vital industries. They cite the expectation of technology transfer held over Western companies who want access to China’s explosive domestic market. Many Chinese nationals employed by American pharmaceutical firms have stolen trade secrets and provided them to Chinese companies. Plus, China is heavily involved in cyber-espionage to steal treatment protocols, manufacturing plant specifications, and cost and pricing data to undercut U.S. companies and co-opt government-funded research.
It’s not just the carcinogens in your blood pressure medications. The game is much bigger.
Is Your Generic Medication Made In China and Is It Safe?
Where Are My Generics Medications Made? India, China, or the US?
Science Daily article here. Study abstract here.
Conclusions
MD lowered the risk of all-cause, cardiovascular and CAD/cerebrovascular mortality CVD patients, net of statins. In the same population, statins reduced CVD death risk only in combination with MD. Low-grade inflammation, rather than lipids, is likely to be on the pathway of the interaction between MD and statins towards mortality risk.
Bloodwork was supposed to be the last step in Isela’s application for life insurance. But when she arrived at the lab, her appointment had been canceled. “That was my first warning,” Isela said. She contacted her insurance agent and was told her application was denied because something on her medication list indicated that Isela uses…
via Nurse Denied Life Insurance Because She Carries Naloxone — Kaiser Health News
There are days when I’m so glad I am no longer in a management role.
Today is one of those days.
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