FDA Should Ban Retail Sale of Bulk Caffeine – Center for Science in the Public Interest

FDA Should Ban Retail Sale of Bulk Caffeine, Says CSPI ~ Newsroom ~ News from CSPI ~ Center for Science in the Public Interest.

Just a teaspoon of powdered caffeine is equivalent to about 25 cups of coffee.

Sacrificing people for profits.  I think I’ll mix some caffeine powder in my energy drink.

Snorting bupropion – The Poison Review

Snorting bupropion | The Poison Review.

The abuse of bupropion by pulverizing and snorting the medication has been described at least as far back as 2002. Bupropion inhibits re-uptake of dopamine and norepinephrine, but apparently has little or no effect on serotonin. It is abused for its psychotropic effects that resemble those of amphetamine and cocaine..

A hallmark of overdose with sustained-release or extended-release bupropion formulations is delayed onset of seizures — sometimes more than 8 hours after ingestion. When these preparations are crushed and insufflated, absorption is rapid and manifestations would be expected to come on more quickly.

– See more at: http://www.thepoisonreview.com/2014/11/12/snorting-bupropion/#sthash.35NLtujG.dpuf

Neurotoxicity with Antimicrobials in the Elderly: A Review – Clinical Therapeutics

Yikes!

Neurotoxicity with Antimicrobials in the Elderly: A Review – Clinical Therapeutics.

Findings

Various antimicrobial classes are implicated with neurotoxicity. The classes with the most reported cases include fluoroquinolones, macrolides, sulfonamides, nitrofurans, and β-lactams. A higher risk of developing various symptoms of neurotoxicity was found in the elderly with use of piperacillin and tazobactam, cephalosporins, carbapenems, aminoglycosides, trimethoprim and sulfamethoxazole, nitrofurantoin, linezolid, and possibly the fluoroquinolones. Potential mechanisms of neurotoxicity differ between the agents. The etiology of neurotoxicity with some agents is not fully elucidated. Incidence may increase with reported risk factors, renal dysfunction, or drug interactions.