There are multiple links in the WP article to the original studies.
Pharma
FDA Stiffens Warning on NSAID Cardiovascular Risk | Medpage Today
FDA Stiffens Warning on NSAID Cardiovascular Risk | Medpage Today.
Thought I would add a link to the actual FDA alert.
NSAIDs can increase the risk of heart attack or stroke in patients with or without heart disease or risk factors for heart disease. A large number of studies support this finding, with varying estimates of how much the risk is increased, depending on the drugs and the doses studied.
PCSK9 Inhibitors
There’s also the issue of cost. The medicines are expected to come with a price tag of $7,000 to $12,000 per patient per year, according to the Wall Street Journal’s Pharmalot blog, costing the US health system as much as $23 billion a year. “These injectable drugs are already viewed by payers as potential budget busters along the lines of treatments for hepatitis C and some cancers,” Ed Silverman wrote.
via There’s still a lot we don’t know about the new cholesterol-lowering drugs – Vox.
PodMed – Johns Hopkins 05.09.15 Medpage Today
PodMed: A Medical News Roundup From Johns Hopkins | Medpage Today.
Digoxin and mortality at the six minute mark of the podcast is a must listen.
Hemodialysis in Metformin Poisoning | The Poison Review
According to some reports metformin poisoning, though rare, is associated with a mortality rate of 30%.
via Hemodialysis in metformin poisoning | The Poison Review.
Yikes.
Intensive Tx Fails to Slow Atherosclerosis | Medpage Today
“When we see something that surprises us and flies in the face of what is understood, it requires another look — maybe a different cohort, larger numbers, longer follow-up,”
via Intensive Tx Fails to Slow Atherosclerosis | Medpage Today.
Surprised? As long as we continue to focus on pharmaceuticals as the answer, no one should be surprised.
Should patients stop taking aspirin for primary prevention? : Cleveland Clinic Journal of Medicine
More on the aspirin debate.
Should patients stop taking aspirin for primary prevention? : Cleveland Clinic Journal of Medicine.
Stroke Rounds: Opioids Linked to Afib | Medpage Today
Killing Pain: Benzo ‘Boost’ Can Be Deadly | Medpage Today
Workers Seeking Productivity in a Pill Are Abusing A.D.H.D. Drugs – NYTimes.com
A 2013 report by the federal Substance Abuse and Mental Health Services Administration found that emergency room visits related to nonmedical use of prescription stimulants among adults 18 to 34 tripled from 2005 to 2011, to almost 23,000.
via Workers Seeking Productivity in a Pill Are Abusing A.D.H.D. Drugs – NYTimes.com.
“It is necessary — necessary for survival of the best and the smartest and highest-achieving people.”
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