If Your Leg Breaks Stop Taking Biphosphonates

The highlighted bold is me.  I keep reading this FDA recommendation just to make sure I understand what they are trying to say.  I think the recommendation says the FDA found no cause and effect between the use of biphosphonates and leg fractures so keep taking your medication.  But if your leg breaks, your physician will instruct you to stop taking the medication she prescribed for you to help prevent bone loss and fractures.

I’m glad the FDA cleared up this issue, don’t you?

Safety Alerts for Human Medical Products > Bisphosphonates (Osteoporosis Drugs): Label Change – Atypical Fractures Update

BACKGROUND: Atypical subtrochanteric femur fractures are fractures in the bone just below the hip joint. Diaphyseal femur fractures occur in the long part of the thigh bone. These fractures are very uncommon and appear to account for less than 1% of all hip and femur fractures overall. Although it is not clear if bisphosphonates are the cause, these unusual femur fractures have been predominantly reported in patients taking bisphosphonates.

RECOMMENDATIONS: Patients should continue to take their medication unless told to stop by their healthcare professional. FDA recommends that healthcare professionals should discontinue potent antiresorptive medications (including bisphosphonates) in patients who have evidence of a femoral shaft fracture. See the FDA Drug Safety Communication below for additional information.

FDA Warns Docs, Patients of Femoral Fracture Risk Linked to Some Bisphosphonates — AAFP News Now — American Academy of Family Physicians

Wrapper Products

Switzerland Threatens Tax Cheats Using ‘Wrappers’ (Update1) – Bloomberg.com

When a client buys a wrapper, the beneficial ownership of the assets is transferred to the insurer while the funds often remain on the balance sheet of private banks. Insurers invest the premiums through advisers and clients receive benefits tied to the performance of the underlying investment. Taxes are minimized or deferred because life insurance policies are classified as non-income producing assets.