underwriting

Epilepsy Increases Mortality Risk in Pregnant Women | Medpage Today

/ SupremeCmdr / Leave a comment

Sarah C. MacDonald, BSc, of the Harvard T. H. Chan School of Public Health, and colleagues, found that after adjusting for several confounders, women with epilepsy had a more than 10-fold increased risk of death during delivery hospitalization (adjusted odds ratio 11.46, 95% CI 8.64-15.19) compared with women without epilepsy (80 deaths per 100,000 pregnancies versus six deaths in 100,000 pregnancies).

via Epilepsy Increases Mortality Risk in Pregnant Women | Medpage Today.

FDA Stiffens Warning on NSAID Cardiovascular Risk | Medpage Today

/ SupremeCmdr / Leave a comment

FDA Stiffens Warning on NSAID Cardiovascular Risk | Medpage Today.

Thought I would add a link to the actual FDA alert.

via Safety Alerts for Human Medical Products > Non-aspirin Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Drug Safety Communication – FDA Strengthens Warning of Increased Chance of Heart Attack or Stroke.

NSAIDs can increase the risk of heart attack or stroke in patients with or without heart disease or risk factors for heart disease. A large number of studies support this finding, with varying estimates of how much the risk is increased, depending on the drugs and the doses studied.

PCSK9 Inhibitors

/ SupremeCmdr / Leave a comment

There’s also the issue of cost. The medicines are expected to come with a price tag of $7,000 to $12,000 per patient per year, according to the Wall Street Journal’s Pharmalot blog, costing the US health system as much as $23 billion a year. “These injectable drugs are already viewed by payers as potential budget busters along the lines of treatments for hepatitis C and some cancers,” Ed Silverman wrote.

via There’s still a lot we don’t know about the new cholesterol-lowering drugs – Vox.