Variants of ‘Redhead’ Gene Up Melanoma Risk Even Without Sun

This case-control study investigates the association between the presence of MC1R variants and melanoma risk independent of sun exposure.

Source: JAMA Network | JAMA Dermatology | Human Determinants and the Role of Melanocortin-1 Receptor Variants in Melanoma Risk Independent of UV Radiation Exposure

Source: Variants of ‘Redhead’ Gene Up Melanoma Risk Even Without Sun

Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease — NEJM

Conclusions: Treatment with rosuvastatin at a dose of 10 mg per day resulted in a significantly lower risk of cardiovascular events than placebo in an intermediate-risk, ethnically diverse population without cardiovascular disease. (Funded by the Canadian Institutes of Health Research and AstraZeneca; HOPE-3 ClinicalTrials.gov number, NCT00468923.)

Source: Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease — NEJM

Source: Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease — NEJM

Source: Blood-Pressure and Cholesterol Lowering in Persons without Cardiovascular Disease — NEJM

How to roll a joint video: 10 easy steps to roll the perfect joint

One of legal cannabis’ tremendously modern luxuries is the pre-roll joint. No longer do you have to buy sub-par product from your dealer, work the seeds-and-stems quality control, grind it up and roll your own joint. Now you can walk into a store and purchase a pre-roll — or a package of pre-rolls. You can mix-and-match different strain pre-rolls. Some shops let you choose between the regular and mini-joints. And some will even offer an option wrapped in 24K gold rolling papers.

Source: How to roll a joint video: 10 easy steps to roll the perfect joint

Times have changed, no?

CardioBrief: Studies Spotlight Triglycerides, Put HDL in the Shade | Medpage Today

Two new studies provide more evidence tilting the balance in favor of triglycerides, rather than HDL, playing a causative role in cardiovascular disease. But it is still too early to know whether the findings of any of the studies will point to useful new methods to prevent and treat disease.

Source: CardioBrief: Studies Spotlight Triglycerides, Put HDL in the Shade | Medpage Today

There are links to other studies at the end of this Medpage article.

Take Home – Do not ignore triglycerides.