Circulating TNF Receptors 1 and 2 Predict ESRD in Type 2 Diabetes.
Circulating TNF Receptors 1 and 2 Predict Stage 3 CKD in Type 1 Diabetes.
Watch those TNF receptors!
underwriting
Glass of Wine Eases Stroke Risk in Women
A study of more than 80,000 women found that low to moderate alcohol consumption was associated with a 17% to 21% reduction in risk of stroke.
Minor Trauma Led to Death in Pradaxa Patient
Dabigatran etexilate is an oral anticoagulant that acts as a direct, competitive thrombin inhibitor. It does not require routine monitoring and has been approved by the FDA for the prevention of stroke and systemic embolism in patients with atrial fibrillation. Note, however, that no effective reversal agent for dabigatran in the event of catastrophic hemorrhage has been identified.
On the article’s webpage you’ll find a link to download a PDF copy of the source article.
Mortality Risk Quantified for Diabetes Plus Kidney Disease
This meta-analysis found that the presence of chronic kidney disease strongly predicted mortality risk in patients with type 2 diabetes. Chronic kidney disease more than doubles mortality risk in patients with type 2 diabetes, researchers found. In an analysis of nearly two dozen randomized controlled trials involving diabetic patients, the highest mortality rates were observed in those trials that required the inclusion of patients with renal disease, according to Marc Pfeffer, MD, PhD, of Brigham and Women’s Hospital in Boston, and colleagues. Trials that selected for patients with elevated serum creatinine or impaired estimated glomerular filtration rate eGFR had mortality rates of 5.9 to 8.2 per 100 patient-years, whereas the rest of the trials had rates no higher than 3.3, the researchers reported online in the Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease.
Duration of Diabetes Raises Stroke Risk
Diabetes at baseline and duration of diabetes both significantly increased the risk of an ischemic stroke, according to a longitudinal study. Having diabetes for 10 years or more tripled the risk of an ischemic stroke in this racially and ethnically diverse population.
via Medical News:Duration of Diabetes Raises Stroke Risk – in Cardiovascular, Strokes from MedPage Today.
FDA Adds Diabetes Warning to Statin Labels
The diabetes warning has been rumored as a possibility since the findings from the JUPITER trial of rosuvastatin revealed an unexpected 27% increase in new onset diabetes among patients randomized to the statin.That finding was especially perplexing because JUPITER was a study of statins in patients who had no history of cardiovascular disease, the so-called healthy patient trial. Moreover, based on the JUPITER results, the FDA approved rosuvastatin for primary prevention.The FDA said hyperglycemia was also observed among patients treated with 40-mg atorvastatin in a substudy of PROVE-IT TIMI 22, and a meta-analysis of data from 13 statin trials “reported that statin therapy was associated with a 9% increased risk for incident diabetes.”
Inhaled Steroids Lower Pneumonia Mortality in COPD Patients
Of 15,768 eligible patients with COPD who were hospitalized for pneumonia, 8271 had prior ICS use and 7497 had no ICS use. Compared with patients with no prior ICS use, those with prior ICS use had a lower 90-day mortality rate 17.3% vs 22.8%; P < .001.
via Inhaled Steroids Lower Pneumonia Mortality in COPD Patients.
Effect of Aspirin on Vascular and Nonvascular Outcomes Meta-analysis
Conclusion: Despite important reductions in nonfatal MI, aspirin prophylaxis in people without prior CVD does not lead to reductions in either cardiovascular death or cancer mortality. Because the benefits are further offset by clinically important bleeding events, routine use of aspirin for primary prevention is not warranted and treatment decisions need to be considered on a case-by-case basis.
MIB Life Index January 2012 +8.3%
Life Index | MIB Solutions, Inc. | The Industry’s Timeliest Measure of Application Activity.
This is encouraging news.
Latin America: Where the world’s jobs are
Latin America: Where the world’s jobs are – CSMonitor.com.
So far, 200 entrepreneurs from 30 different countries have traveled to Chile to try to get their ideas off the ground through Start-Up Chile. The program aims to fund 1,000 entrepreneurs by 2014, and not only benefits the grantees – 80 percent of whom are foreigners – but is a boon to Chile, too, says spokeswoman Brenna Loury.
Interesting little article that offers minimal facts to back up the author’s assertion in the title. How does 200 entrepreneurs equal “where the world’s jobs are”?
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