Byetta (exenatide) – Renal Failure
From April 2005 through October 2008, FDA received 78 cases of altered kidney function (62 cases of acute renal failure and 16 cases of renal insufficiency), in patients using Byetta. Some cases occurred in patients with pre-existing kidney disease or in patients with one or more risk factors for developing kidney problems.
Oops.CRP concentration has continuous associations with the risk of coronary heart disease, ischaemic stroke, vascular mortality, and death from several cancers and lung disease that are each of broadly similar size. The relevance of CRP to such a range of disorders is unclear. Associations with ischaemic vascular disease depend considerably on conventional risk factors and other markers of inflammation.
Research Project – Automated Life Underwriting
The link takes you to the SOA website page where the full report can be downloaded.
The researchers identified 190 pg/mL as the NT-proBNP threshold for increased risk. Among study participants with baseline levels less than 190 pg/mL, an increase greater than 25% to a level above 190 pg/mL had a twofold increased risk of heart failure (HR 2.13, 95% CI 1.68 to 2.71) and cardiovascular death (HR 1.91, 95% CI 1.43 to 2.53) compared with participants whose NT-proBNP levels remained below 190 pg/mL.
Among study participants with elevated baseline NT-proBNP levels, an increase greater than 25% also doubled the risk of heart failure (HR 2.06, 95% CI 1.56 to 2.72) and cardiovascular disease (HR 1.88, 95% CI 1.37 to 2.57).
Please tell me you already knew this.
People with non-alcoholic fatty liver disease (NAFLD), a condition that often accompanies obesity and type 2 diabetes, have higher mortality rates than the general population, a new Swedish study found.
Patients with NAFLD were 69% percent more likely to die than the general Swedish population (standardized mortality ratio 1.69, 95% CI 1.24 to 2.25), according to a report in the February issue of Hepatology.
Patients with non-alcoholic steatohepatitis (NASH), a condition where fat buildup causes liver inflammation, were at 86% higher risk (95% CI 1.19 to 2.76; P=0.007).
Oops.
Sibutramine is not to be used in patients with a history of cardiovascular disease, including:
* History of coronary artery disease (e.g., heart attack, angina)
* History of stroke or transient ischemic attack (TIA)
* History of heart arrhythmias
* History of congestive heart failure
* History of peripheral arterial disease
* Uncontrolled hypertension (e.g., > 145/90 mmHg)
This is not good.
Prevalence of Abnormal Lipid Levels Among Youths — United States, 1999–2006
In 1999–2006, 20.3% of youths aged 12–19 years had abnormal lipids. A total of 32% were overweight or obese, making them eligible for lipid screening under American Academy of Pediatrics (AAP) guidelines based solely on their BMI.
I found the following in my email this morning. Good luck if you’re looking for work.
We value your continued interest and would welcome the opportunity to speak with you or any referrals that are a match for our projects. If we do not have your current resume on file, please email it to us at dshay@jacobsononline.com or lsalem@jacobsononline.com.
We will be in contact regarding future projects. Please do not hesitate to pass along our contact information; we are always appreciative of referrals.
Warm regards,
Diana Shay
Fulfillment Manager
Direct Dial: (312) 884-0424
Lauren Salem
Client Service Manager
Direct Dial: (312) 884-0443
The Jacobson Group
120 South LaSalle Street, Suite 1410
Chicago, Illinois 60603
Toll Free: (800) 466-1578
www.jacobsononline.com
| Life | This established insurance corporation has a need for multiple life underwriters with extensive BGA experience. Our client requires that these consultants have a minimum signing authority of $3 million. | TBD, Estimate is 4-6 months | Remote |
lifeunderwriter.net 
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